Evidence map›Paper›PMID 28971090›Full record

ArticleClinical and translational imaging2017

Molecular imaging and fusion targeted biopsy of the prostate.

Baowei Fei, Peter T Nieh, Viraj A Master, Yun Zhang, Adeboye O Osunkoya, David M Schuster

Abstract read
In one paragraph

Article in Clinical and translational imaging, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. European journal of nuclear medicine and molecular imaging · 2021
    Trial
  3. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2019
    Trial
  4. Trial
  5. Article
  6. Automatic Segmentation of the Prostate on MR Images based on Anatomy and Deep Learning.Proceedings of SPIE--the International Society for Optical Engineering · 2021
    Article
  7. Article
  8. La Radiologia medica · 2018
    Review
  9. PET Molecular Imaging-Directed Biopsy: A Review.AJR. American journal of roentgenology · 2017
    Review
  10. Article
  11. Review
  12. An Augmented Reality-Assisted Visualization System for Potential Applications in Prostate Biopsy.Proceedings of SPIE--the International Society for Optical Engineering
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Baowei FeiDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA.
Peter T NiehDepartment of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Viraj A MasterDepartment of Urology, Emory University School of Medicine, Atlanta, GA 30322, USA.
Yun ZhangDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA.
Adeboye O OsunkoyaWinship Cancer Institute of Emory University, Atlanta, GA 30329, USA.
David M SchusterDepartment of Radiology and Imaging Sciences, Emory University School of Medicine, 1841 Clifton Road NE, Atlanta, GA 30329, USA.

Funding

ACADEMIC-INDUSTRIAL PARTNERSHIP FOR TRANSLATION OF PET/TRUS GUIDED INTERVENTIONR01CA204254 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2017 to 2021
$2.0M
MOLECULAR IMAGING DIRECTED, 3D ULTRASOUND-GUIDED, BIOPSY SYSTEMR01CA156775 · NCI · UNIVERSITY OF TEXAS DALLAS · PI FEI, BAOWEI · 2011 to 2016
$1.7M
Targeted fusion biopsy using anti-[18F]FACBC PET/CT and real-time 3D ultrasound gR21CA176684 · NCI · EMORY UNIVERSITY · PI FEI, BAOWEI, MASTER, VIRAJ · 2013 to 2014
$568k
Multimodality in vivo Molecular Imaging for Prostate PDTR21CA120536 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI FEI, BAOWEI · 2006 to 2007
$326k
NCI NIH HHS R01 CA156775NCI NIH HHS R01 CA204254NCI NIH HHS R21 CA120536NCI NIH HHS R21 CA176684
6 · The paper itself

Abstract

purposeThis paper provides a review on molecular imaging with positron emission tomography (PET) and magnetic resonance imaging (MRI) for prostate cancer detection and its applications in fusion targeted biopsy of the prostate.

methodsLiterature search was performed through the PubMed database using the keywords "prostate cancer", "MRI/ultrasound fusion", "molecular imaging", and "targeted biopsy". Estimates in autopsy studies indicate that 50% of men older than 50 years of age have prostate cancer. Systematic transrectal ultrasound (TRUS) guided prostate biopsy is considered the standard method for prostate cancer detection and has a significant sampling error and a low sensitivity. Molecular imaging technology and new biopsy approaches are emerging to improve the detection of prostate cancer.

resultsMolecular imaging with PET and MRI shows promising results in the early detection of prostate cancer. MRI/TRUS fusion targeted biopsy has become a new clinical standard for the diagnosis of prostate cancer. PET molecular image-directed, three-dimensional ultrasound-guided biopsy is a new technology that has great potential for improving prostate cancer detection rate and for distinguishing aggressive prostate cancer from indolent disease.

conclusionMolecular imaging and fusion targeted biopsy are active research areas in prostate cancer research.

Indexed as

Image registrationImage segmentationMagnetic resonance imaging (MRI)Molecular imagingPositron emission tomography (PET)Prostate cancerTargeted biopsy

Identifiers

PMID28971090
PMCPMC5621648

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.