Evidence map›Paper›PMID 28971062›Full record

ArticleFrontiers in oncology2017

Cancers Attributable to Alcohol Consumption in Nigeria: 2012-2014.

Michael Kolawole Odutola, Elima E Jedy-Agba, Eileen O Dareng, Sally N Adebamowo, Emmanuel A Oga, Festus Igbinoba, Theresa Otu, Emmanuel Ezeome, Ramatu Hassan, Clement A Adebamowo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 8 institutions in 3 countries.

Michael Kolawole OdutolaInstitute of Human Virology, Abuja, Nigeria.
Elima E Jedy-AgbaInstitute of Human Virology, Abuja, Nigeria.
Eileen O DarengCenter for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom.
Sally N AdebamowoDepartment of Epidemiology and Public Health, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, United States.
Emmanuel A OgaBattelle Memorial Institute, Baltimore, MD, United States.
Festus IgbinobaNational Hospital Abuja, Abuja, Nigeria.
Theresa OtuUniversity of Abuja Teaching Hospital, Gwagwalada, Nigeria.
Emmanuel EzeomeUniversity of Nigeria Teaching Hospital, Enugu, Nigeria.
Ramatu HassanFederal Ministry of Health, Abuja, Nigeria.
Clement A AdebamowoInstitute of Human Virology, Abuja, Nigeria.
Institute of Human Virology · NGBattelle · USFederal Ministry of Health · NGNational Hospital Abuja · NGUniversity of Abuja Teaching Hospital · NGUniversity of Cambridge · GBUniversity of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer CenterUniversity of Nigeria Teaching Hospital · NG

Funding

African Collaborative Center for Microbiome and Genomics Research (ACCME)U54HG006947 · NHGRI · INSTITUTE OF HUMAN VIROLOGY · PI ADEBAMOWO, CLEMENT ADEBAYO · 2013 to 2018
$5.7M
Capacity Development for Research into AIDS Associated malignancies (CADRE)D43CA153792 · NCI · UNIVERSITY OF MARYLAND BALTIMORE · PI ADEBAMOWO, CLEMENT ADEBAYO · 2010 to 2013
$1.8M
NCI NIH HHS D43 CA153792NHGRI NIH HHS U54 HG006947
6 · The paper itself

Abstract

introductionAlcohol consumption has been identified as a risk factor for many cancers but less attention has been paid to the fraction of those cancers that are attributable to alcohol consumption. In this study, we evaluated the incidence and population attributable fraction (PAF) of cancers associated with alcohol consumption in Nigeria.

methodsWe obtained data on incidence of cancers from two population-based cancer registries (PBCRs) in Nigeria and identified cancer sites for which there is strong evidence of an association with alcohol consumption based on the International Agency for Research on Cancer Monograph 100E. We computed the PAF for each cancer site by age and sex, using prevalence and relative risk estimates from previous studies.

resultsBetween 2012 and 2014 study period, the PBCRs reported 4,336 cancer cases of which 1,627 occurred in males, and 2,709 occurred in females. Of these, a total of 1,808 cancer cases, 339 in males and 1,469 in females, were associated with alcohol intake. The age standardized incidence rate (ASR) of alcohol associated cancers was 77.3 per 100,000. Only 4.3% (186/4,336) of all cancer cases or 10.3% (186/1,808) of alcohol associated cancers were attributable to alcohol consumption. Some 42.5% (79/186) of these cancers occurred in males while 57.5% (107/186) occurred in females. The ASR of cancers attributable to alcohol in this population was 7.2 per 100,000. The commonest cancers attributable to alcohol consumption were cancers of the oral cavity and pharynx in men and cancer of the breast in women.

conclusionOur study shows that 4.3% of incident cancers in Nigeria can be prevented by avoiding alcohol consumption. While the incidence of cancers associated with alcohol intake is high, the proportion attributable to alcohol consumption is much lower suggesting that the number of cancers that may be prevented by eliminating alcohol intake in this population is relatively low.

Indexed as

alcoholassociated cancersattributable cancerscancercancer registryNigeria

Identifiers

PMID28971062
PMCPMC5609586
OpenAlexW2746631632

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.