Evidence map›Paper›PMID 28970943›Full record

ArticleNPJ biofilms and microbiomes2017

Towards individualized diagnostics of biofilm-associated infections: a case study.

Mathias Müsken, Kathi Klimmek, Annette Sauer-Heilborn, Monique Donnert, Ludwig Sedlacek, Sebastian Suerbaum, Susanne Häussler

Abstract read
In one paragraph

Article in NPJ biofilms and microbiomes, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Frontiers in cellular and infection microbiology · 2022
    Article
  5. Transcriptional Profiling of Pseudomonas aeruginosa Infections.Advances in experimental medicine and biology · 2022
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Predicting Antibiotic-Associated Virulence ofFrontiers in microbiology · 2020
    Article
  12. Parallel evolutionary paths to produce more than oneNPJ biofilms and microbiomes · 2020
    Article
  13. IL-1β PromotesFrontiers in immunology · 2019
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mathias MüskenInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Kathi KlimmekInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Annette Sauer-HeilbornDepartment of Pulmonary Medicine, Hannover Medical School, Hannover, Germany.
Monique DonnertInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.
Ludwig SedlacekInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Sebastian SuerbaumInstitute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany.
Susanne HäusslerInstitute for Molecular Bacteriology, TWINCORE, Centre for Experimental and Clinical Infection Research, Hannover, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Organized within biofilm communities, bacteria exhibit resistance towards a broad spectrum of antibiotics. Thus, one might argue that bacteria isolated from biofilm-associated chronic infections should be subjected to resistance profiling under biofilm growth conditions. Various test systems have been developed to determine the biofilm-associated resistance; however, it is not clear to what extent the in vitro results reflect the situation in vivo, and whether the biofilm-resistance profile should guide clinicians in their treatment choice. To address this issue, we used confocal microscopy in combination with live/dead staining, and profiled biofilm-associated resistance of a large number (>130) of clinical

Identifiers

PMID28970943
PMCPMC5620081

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.