Evidence map›Paper›PMID 28970851›Full record

ArticleJournal of breast cancer2017

Prognostic Influence of Preoperative Fibrinogen to Albumin Ratio for Breast Cancer.

Ki-Tae Hwang, Jung Kee Chung, Eun Youn Roh, Jongjin Kim, Sohee Oh, Young A Kim, Jiyoung Rhu, Suzy Kim

Open access · goldAbstract read
In one paragraph

Article in Journal of breast cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
3.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 76 citations in OpenAlex.

  1. Pooled it
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    Pooled it
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  15. Association between fibrinogen-to-albumin ratio and hemorrhagic transformation after intravenous thrombolysis in ischemic stroke patients.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
    Article
  16. Transcriptomic Profile of Canine Mammary Ductal Carcinoma.International journal of molecular sciences · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ki-Tae HwangDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Jung Kee ChungDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Eun Youn RohDepartment of Laboratory Medicine, Seoul National University Boramae Medical Center, Seoul, Korea.
Jongjin KimDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Sohee OhDepartment of Biostatistics, Seoul National University Boramae Medical Center, Seoul, Korea.
Young A KimDepartment of Pathology, Seoul National University Boramae Medical Center, Seoul, Korea.
Jiyoung RhuDepartment of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea.
Suzy KimDepartment of Radiation Oncology, Seoul National University Boramae Medical Center, Seoul, Korea.
Seoul National University · KRSNUH SMG-SNU Boramae Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeElevated serum concentration of fibrinogen and decreased serum concentration of albumin have been reported to be markers of elevated systemic inflammation. We attempted to investigate the prognostic influence of preoperative fibrinogen to albumin ratio (FAR) for breast cancer.

methodsData from 793 consecutive primary breast cancer patients were retrospectively analyzed. Serum levels of fibrinogen and albumin were tested before curative surgery. Subjects were grouped into two groups according to the cutoff value determined by performing the receiver operating characteristic curve analysis: the high FAR group (FAR>7.1) and the low FAR group (FAR≤7.1). Overall survival was assessed using the Kaplan-Meier estimator. Independent prognostic significance was analyzed using the Cox proportional hazards model.

resultsThe high FAR group had a worse prognosis compared to the low FAR group (log-rank test,

conclusionPreoperative FAR was a strong independent prognostic factor in breast cancer. Its prognostic effect was more prominent in the stage II/III subgroup and in the luminal A-like subtype. Therefore, preoperative FAR can be utilized as a useful prognosticator for breast cancer patients. Further studies are needed to validate its applications in clinical settings.

Indexed as

Breast neoplasmsFibrinogenPrognosisSerum albuminSurvival analysis

Identifiers

PMID28970851
PMCPMC5620440
OpenAlexW2758869972

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.