Evidence map›Paper›PMID 28970777›Full record

ReviewFood & nutrition research2017

Anthocyanidins and anthocyanins: colored pigments as food, pharmaceutical ingredients, and the potential health benefits.

Hock Eng Khoo, Azrina Azlan, Sou Teng Tang, See Meng Lim

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Food & nutrition research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07114341 (Effect of Lyophilized Cornelian Cherry on Anaerobic Performance in Young Football Players), which is not on this map. Cited by 880 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
880citing papers in PubMed, 3 pooled it
61.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07114341 nacompletednot on this mapstarted 2025, after this paper: background citation

Effect of Lyophilized Cornelian Cherry on Anaerobic Performance in Young Football Players

TypeinterventionalSponsorIstanbul Bilgi UniversityRan2025 to 2025Enrolled50ConditionsSport Nutrition, Sports Performance in Children, Ergogenic Athletic Performance, Ergogenic SupportArmsCranberry Intervention
3 · Its place in the literature

Who cites it

880 citing papers in PubMed, 3 syntheses or guidelines pooled it, 2,776 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Trial
  5. International journal of medical sciences · 2026
    Trial
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  16. Ethnobotany-guided exploration of plant-derived photosensitizer candidates for photodynamic therapy.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Review
  17. Article
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  19. Review
  20. Article

820 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Hock Eng KhooDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia.ORCID 0000-0002-7686-6092
Azrina AzlanDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia.ORCID 0000-0002-5373-0985
Sou Teng TangDepartment of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Selangor Darul Ehsan, Malaysia.ORCID 0000-0002-1733-4352
See Meng LimNutritional Sciences Program, School of Healthcare Science, Faculty of Health Sciences, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia.ORCID 0000-0002-8983-9245
Universiti Putra Malaysia · MYNational University of Malaysia · MY

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anthocyanins are colored water-soluble pigments belonging to the phenolic group. The pigments are in glycosylated forms. Anthocyanins responsible for the colors, red, purple, and blue, are in fruits and vegetables. Berries, currants, grapes, and some tropical fruits have high anthocyanins content. Red to purplish blue-colored leafy vegetables, grains, roots, and tubers are the edible vegetables that contain a high level of anthocyanins. Among the anthocyanin pigments, cyanidin-3-glucoside is the major anthocyanin found in most of the plants. The colored anthocyanin pigments have been traditionally used as a natural food colorant. The color and stability of these pigments are influenced by pH, light, temperature, and structure. In acidic condition, anthocyanins appear as red but turn blue when the pH increases. Chromatography has been largely applied in extraction, separation, and quantification of anthocyanins. Besides the use of anthocyanidins and anthocyanins as natural dyes, these colored pigments are potential pharmaceutical ingredients that give various beneficial health effects. Scientific studies, such as cell culture studies, animal models, and human clinical trials, show that anthocyanidins and anthocyanins possess antioxidative and antimicrobial activities, improve visual and neurological health, and protect against various non-communicable diseases. These studies confer the health effects of anthocyanidins and anthocyanins, which are due to their potent antioxidant properties. Different mechanisms and pathways are involved in the protective effects, including free-radical scavenging pathway, cyclooxygenase pathway, mitogen-activated protein kinase pathway, and inflammatory cytokines signaling. Therefore, this review focuses on the role of anthocyanidins and anthocyanins as natural food colorants and their nutraceutical properties for health.

Indexed as

Anthocyanincolorantdiseasehealth benefitpigment

Identifiers

PMID28970777
PMCPMC5613902
OpenAlexW2747068608

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.