Evidence map›Paper›PMID 28970729›Full record

ArticleWorld journal of gastroenterology2017

Patients with inflammatory bowel disease have increased risk of autoimmune and inflammatory diseases.

Morten L Halling, Jens Kjeldsen, Torben Knudsen, Jan Nielsen, Lars Koch Hansen

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of gastroenterology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 8 pooled it
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 8 syntheses or guidelines pooled it, 226 citations in OpenAlex.

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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Morten L HallingDepartment of Gastroenterology and Hepatology, Hospital of Southwest Jutland, 6700 Esbjerg, Denmark. mortenhalling@gmail.com.
Jens KjeldsenDepartment of Medical Gastroenterology S, Odense University Hospital, 5000 Odense, Denmark.
Torben KnudsenDepartment of Gastroenterology and Hepatology, Hospital of Southwest Jutland, 6700 Esbjerg, Denmark.
Jan NielsenCenter for Clinical Epidemiology, Odense University Hospital, 5000 Odense, Denmark.
Lars Koch HansenDepartment of Medical Gastroenterology S, Odense University Hospital, 5000 Odense, Denmark.
Odense University Hospital · DKHospital South West Jutland · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo investigate whether immune mediated diseases (IMD) are more frequent in patients with inflammatory bowel disease (IBD).

methodsIn this population based registry study, a total of 47325 patients with IBD were alive and registered in the Danish National Patient Registry on December 16, 2013. Controls were randomly selected from the Danish Civil Registration System (CRS) and matched for sex, age, and municipality. We used ICD 10 codes to identify the diagnoses of the included patients. The IBD population was divided into three subgroups: Ulcerative colitis (UC), Crohn's disease (CD) and Both the latter referring to those registered with both diagnoses. Subsequently, odds-ratios (OR) and 95%CI were obtained separately for each group and their respective controls. The use of Bonferoni post-test correction adjusted the significance level to

resultsThere were significantly more women than men in the registry, and a greater percentage of comorbidity in the IBD groups (

conclusionImmune mediated diseases were significantly more frequent in patients with IBD. Our results strengthen the hypothesis that some IMDs and IBD may have overlapping pathogenic pathways.

Indexed as

Autoimmune DiseasesColitis, UlcerativeComorbidityCrohn DiseaseCross-Sectional StudiesDenmarkFemaleHumansInflammationMaleMiddle AgedOdds RatioRegistriesRisk FactorsSex FactorsAutoimmune diseasesChronic inflammatory diseasesCrohn’s diseaseExtraintestinal manifestationsImmune mediated diseasesInflammatory bowel diseasePrevalenceRegistryRiskUlcerative colitis

Identifiers

PMID28970729
PMCPMC5597505
OpenAlexW2754234518

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.