Evidence map›Paper›PMID 28970715›Full record

ArticleJournal of clinical and experimental hepatology2017

Norethisterone Related Drug Induced Liver Injury: A Series of 3 Cases.

Narendra S Choudhary, Vijay Bodh, Shraddha Chaudhari, Neeraj Saraf, Sanjiv Saigal

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Acute liver injury in pregnancy.BMJ case reports · 2024
    Article
  3. Article
  4. Article
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Narendra S ChoudharyMedanta Liver Institute, Medanta, The Medicity, Gurgaon, Haryana, India.
Vijay BodhFortis Hospital, Kangra, Himachal Pradesh, India.
Shraddha ChaudhariDepartment of Gynaecology & Gynaeconcology, Medanta, The Medicity, Gurgaon, Haryana, India.
Neeraj SarafMedanta Liver Institute, Medanta, The Medicity, Gurgaon, Haryana, India.
Sanjiv SaigalMedanta Liver Institute, Medanta, The Medicity, Gurgaon, Haryana, India.
Medanta The Medicity · INFortis Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Drug induced liver injury (DILI) is uncommon and severe forms are associated with significant morbidity and mortality. Female sex hormones (estrogens and progestogens) related DILI generally occur with estrogen component. Progesterone component related DILI are infrequently reported. Norethisterone is commonly used drug in gynecologic practice to prevent excess per vaginal bleeding. We report 3 cases of Norethisterone related DILI manifesting as significant rise of transaminases. All of these patients took Norethisterone for prolonged periods and improved completely after withdrawal of drug.

Indexed as

ALP, alkaline phosphataseALT, alanine aminotransferaseAST, aspartate aminotransferaseDILI, drug induced liver injurydrug induced liver injuryNorethisteroneprogestogenssex hormonesULN, upper limit of normal

Identifiers

PMID28970715
PMCPMC5620103
OpenAlexW2606671310

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.