Evidence map›Paper›PMID 28970706›Full record

ArticleJournal of clinical and experimental hepatology2017

Brain Microstructural Correlates of Cognitive Dysfunction in Clinically and Biochemically Normal Hepatitis C Virus Infection.

Ajay Kumar, Amar Deep, Rakesh K Gupta, Virendra Atam, Samir Mohindra

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical and experimental hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Brain communications · 2024
    Article
  3. Article
  4. Review
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Ajay KumarDepartment of Medical Gastroenterology, King George's Medical University, Lucknow 226003, India.
Amar DeepExperimental and Public Health Lab, Department of Zoology, University of Lucknow, 226003, India.
Rakesh K GuptaDepartment of Radiodiagnosis, SGPGIMS, Lucknow 226003, India.
Virendra AtamDepartment of Medicine, King George's Medical University, India.
Samir MohindraDepartment of Gastroenterology, SGPGIMS, Lucknow, UP, India.
King George's Medical University · INSanjay Gandhi Post Graduate Institute of Medical Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsThis study examined correlates of the brain's neurocognitive performance among clinically and biochemically normal adult patient with hepatitis C virus (HCV). We hypothesized that anti-HCV positive individuals would demonstrate structural brain abnormalities and neurocognitive dysfunction as well as the changes in cell component and extracellular space in the white matter regions of brain in asymptomatic HCV infection by using diffusion tensor tractrography (DTT) metrics.

methodsAnti-HCV positive patient (

resultsThe patients were subjected to neuroimaging as well as psychological testing. There was no significant difference in basic laboratory parameters in these two groups. Independent

conclusionOur result show that HCV positive individuals would demonstrate structural brain abnormalities and neurocognitive dysfunction as well as the changes in cell component and extracellular space in the white matter regions of brain in asymptomatic HCV infection by using DTT metrics.

Indexed as

BD, block designCC, central cortexCho, cholineDS, digit symbolDTT, diffusion tensor tractrographyFA, fractional anisotrophyFCA, figure connection test AFCB, figure connection test BGln, glutamineGlx, glutamatehepatitis C virusILF, inferior longitudinal fasciculesIns, inositolMD, mean diffusivityMRImyoinsitolNAA, N-acetylaspartateneuropsychometric testsOA, object assemblyPA, picture arrangementPC, picture completionQOL, quality of lifeSLF, superior longitudinal fasciculesSTR fiber bundlesSTR, superior thalamic radiations

Identifiers

PMID28970706
PMCPMC5620352
OpenAlexW2605193144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.