ArticleIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine2017
Pain Measurement in Mechanically Ventilated Patients with Traumatic Brain Injury: Behavioral Pain Tools Versus Analgesia Nociception Index.
Article in Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05313789 (Analgesia Nociception Index for Pain Monitoring in Intensive Care Units), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Analgesia Nociception Index for Pain Monitoring in Intensive Care Units
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pain Measurement in Critically Ill Non-Verbal Patients With Brain Injury: A Systematic Review.Nursing in critical care · 2026Pooled it
- Evaluation of the Analgesia Nociception Index (ANI) as an indicator of discomfort in deeply sedated, prepubescent patients.Journal of clinical monitoring and computing · 2026Article
- Pain assessment using the Analgesia Nociception Index in patients undergoing sedation: a systematic review and meta-analysis.The Korean journal of pain · 2025Article
- Analgesia nociception index and high frequency variability index: promising indicators of relative parasympathetic tone.Journal of anesthesia · 2023Review
- The validity and applications of the analgesia nociception index: a narrative review.Frontiers in surgery · 2023Review
- Reliability of analgesia nociception index (ANI) and surgical pleth index (SPI) during episodes of bleeding - A pilot study.Indian journal of anaesthesia · 2022Article
- Validation of the Critical-Care Pain Observation Tool-Neuro in brain-injured adults in the intensive care unit: a prospective cohort study.Critical care (London, England) · 2021Article
- Newborn infant parasympathetic evaluation for the assessment of analgosedation adequacy in infants treated by mechanical ventilation - a multicenter pilot study.Archives of medical science : AMS · 2021Article
- Observational
- Pain measurement techniques: spotlight on mechanically ventilated patients.Journal of pain research · 2018Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionPain is highly prevalent in critically ill trauma patients, especially those with a traumatic brain injury (TBI). Behavioral pain tools such as the behavioral pain scale (BPS) and critical-care pain observation tool are recommended for sedated noncommunicative patients. Analysis of heart rate variability (HRV) is a noninvasive method to evaluate autonomic nervous system activity. The analgesia nociception index (ANI) device (Physiodoloris
methodsWe performed a prospective observational study in 21 deeply sedated TBI patients. Exclusion criteria were nonsinus cardiac rhythm; presence of pacemaker; atropine or isoprenaline treatment; neuromuscular blocking agents; and major cognitive impairment. Heart rate, blood pressure, and ANI were continuously recorded using the Physiodoloris
resultsIn total, 100 observations were scored. ANI was significantly lower at T2 (Median [min - max] 54.5 [22-100]) compared with T1 (90.5 [50-100], DISCUSSION: Our results suggest that ANI is effective in detecting pain in ventilated sedated TBI patients, including those patients treated with norepinephrine.
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