Evidence map›Paper›PMID 28970561›Full record

ArticleScientific reports2017

Biochemical efficacy, molecular docking and inhibitory effect of 2, 3-dimethylmaleic anhydride on insect acetylcholinesterase.

Kabrambam D Singh, Rajendra K Labala, Thiyam B Devi, Ningthoujam I Singh, Heisnam D Chanu, Sonia Sougrakpam, Bunindro S Nameirakpam, Dinabandhu Sahoo, Yallappa Rajashekar

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 37 citations in OpenAlex.

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  11. The Effect ofInsects · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Kabrambam D SinghInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Rajendra K LabalaDistributed Information Sub-Centre, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Thiyam B DeviInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Ningthoujam I SinghInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Heisnam D ChanuInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Sonia SougrakpamInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Bunindro S NameirakpamInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Dinabandhu SahooMicrobial Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
Yallappa RajashekarInsect Resources Laboratory, Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India. rajacftri@yahoo.co.in.
Institute of Bio-Resources and Sustainable Development · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolution of resistance among insects to action of pesticides has led to the discovery of several insecticides (neonicotinoids and organophosphates) with new targets in insect nervous system. Present study evaluates the mode of inhibition of acetylchlonesterase (AChE), biochemical efficacy, and molecular docking of 2,3-dimethylmaleic anhydride, against Periplaneta americana and Sitophilus oryzae. The knockdown activity of 2,3-dimethylmaleic anhydride was associated with in vivo inhibition of AChE. At KD

Indexed as

AcetylcholinesteraseAmino Acid SequenceAnimalsCatalaseCatalytic DomainCholinesterase InhibitorsDose-Response Relationship, DrugGene ExpressionGlutathioneInsecticidesInsect ProteinsKineticsMaleic AnhydridesMolecular Docking SimulationNervous SystemOryza2,3-dimethylmaleic anhydrideAcetylcholinesteraseCatalaseCholinesterase InhibitorsGlutathioneInsecticidesInsect ProteinsMaleic AnhydridesSuperoxide Dismutase

Identifiers

PMID28970561
PMCPMC5624869
OpenAlexW2756596163

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.