Evidence map›Paper›PMID 28970468›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2017

Prognostic Value of Plasma Long Noncoding RNA ANRIL for In-Stent Restenosis.

Fang Wang, Xi Su, Chengwei Liu, Mingxiang Wu, Bei Li

Open access · hybridAbstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Diabetes and restenosis.Cardiovascular diabetology · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Role of long non-coding RNAs in adipogenesis: State of the art and implications in obesity and obesity-associated diseases.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Review
  11. Article
  12. Article
  13. Non-Coding RNAs as Blood-Based Biomarkers in Cardiovascular Disease.International journal of molecular sciences · 2020
    Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Circulating Long Noncoding RNA LIPCAR Acts as a Novel Biomarker in Patients with ST-Segment Elevation Myocardial Infarction.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  20. Frontiers in endocrinology · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Fang WangDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, Hubei, China (mainland).
Xi SuDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, Hubei, China (mainland).
Chengwei LiuDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, Hubei, China (mainland).
Mingxiang WuDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, Hubei, China (mainland).
Bei LiDepartment of Cardiology, Wuhan Asia Heart Hospital, Wuhan, Hubei, China (mainland).
Wuhan University · CNWuhan Asia Heart Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND In-stent restenosis (ISR) remains a major cause of failure of contemporary percutaneous revascularization therapies. Invasive biomarkers to improve the prognosis of ISR should be considered. This study aimed to investigate the association between plasma ANRIL expression and ISR. MATERIAL AND METHODS A total of 444 patients were included in this research. Serial coronary angiography was performed at baseline (before and after intervention) and within 36 months' follow-up. ISR was defined as >50% diameter stenosis at follow-up. ANRIL expression was quantified using reverse transcription-PCR. An area under the ROC curve (auROC) was generated to assess the diagnostic values of ANRIL. Logistic regression models were used to assess the independent risk factors for ISR. RESULTS Plasma ANRIL expression was significantly increased in patients with ISR, as compared with that in patients without ISR (1.6 [1.1-2.5] vs. 0.9 [0.6-1.3], P<0.001). The auROC (95% confidence interval [CI]) of plasma ANRIL in diagnosing ISR was 0.745 (0.687-0.811). Multiple logistic regression models indicated that drinking (odds ratio [OR]=2.09, 95% CI: 1.08-4.04, P=0.028), hypertension (OR=2.01, 95% CI: 1.14-3.57, P=0.017), diabetes (OR=3.15, 95% CI: 1.63-3.57, P<0.001), low-density lipoprotein (OR=3.14, 95% CI: 1.57-6.31, P=0.001), and ANRIL (OR=2.21, 95% CI: 1.68-2.92, P<0.001) were the independent risk factors for ISR. CONCLUSIONS We found that higher ANRIL expression is associated with ISR, indicating that ANRIL may be an optimal prognostic factor for ISR.

Indexed as

AgedBiomarkersCoronary AngiographyCoronary Artery DiseaseCoronary RestenosisCoronary VesselsDrug-Eluting StentsFemaleHumansMaleMiddle AgedPercutaneous Coronary InterventionPrognosisRetrospective StudiesRisk FactorsRNA, Long NoncodingBiomarkersCDKN2B antisense RNA, humanRNA, Long Noncoding

Identifiers

PMID28970468
PMCPMC5635947
OpenAlexW2763118352

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.