ArticleThe Journal of pharmacology and experimental therapeutics2017
Investigation of Diacylglycerol Lipase Alpha Inhibition in the Mouse Lipopolysaccharide Inflammatory Pain Model.
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Article in The Journal of pharmacology and experimental therapeutics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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19citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Article
- Behavioral Decoding Reveals Cortical Endocannabinoid Potentiation during ΔbioRxiv : the preprint server for biology · 2025Article
- Pharmacological diacylglycerol lipase inhibition impairs contextual fear extinction in mice.Psychopharmacology · 2024Article
- Endocannabinoid biosynthetic enzymes regulate pain response via LKB1-AMPK signaling.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Imaging and Genetic Tools for the Investigation of the Endocannabinoid System in the CNS.International journal of molecular sciences · 2023Review
- Differential roles of diacylglycerol lipase (DAGL) enzymes in nicotine withdrawal.Brain research · 2023Article
- Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years.Pharmacological reviews · 2023Review
- Inhibition of DAGLβ as a therapeutic target for pain in sickle cell disease.Haematologica · 2023Article
- 2-Arachidonoylglycerol-mediated endocannabinoid signaling modulates mechanical hypersensitivity associated with alcohol withdrawal in mice.Alcoholism, clinical and experimental research · 2022Article
- 2-AG and anandamide enhance hippocampal long-term potentiationFrontiers in cellular neuroscience · 2022Article
- Article
- Review
- Traumatic Brain Injury and Alcohol Drinking Alter Basolateral Amygdala Endocannabinoids in Female Rats.Journal of neurotrauma · 2021Article
- Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat.Frontiers in neurology · 2021Article
- Attenuation of fear-conditioned analgesia in rats by monoacylglycerol lipase inhibition in the anterior cingulate cortex: Potential role for CBBritish journal of pharmacology · 2020Article
- Druggable Targets in Endocannabinoid Signaling.Advances in experimental medicine and biology · 2020Review
- Diacylglycerol Lipase-Alpha Regulates Hippocampal-Dependent Learning and Memory Processes in Mice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2019Article
- Role of p120 Catenin in Epac1-Induced Chronic Postsurgical Pain in Rats.Pain research & management · 2019Article
- Broad and Region-Specific Impacts of the Synthetic Cannabinoid CP 55,940 in Adolescent and Adult Female Mouse Brains.Frontiers in molecular neuroscience · 2018Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Jenny L WilkersonDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.) jenny.wilkerson@vcuhealth.org.
Giulia DonvitoDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Travis W GrimDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Rehab A AbdullahDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Daisuke OgasawaraDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Benjamin F CravattDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Aron H LichtmanDepartment of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, Virginia (J.L.W., G.D., T.W.G., R.A.A., A.H.L.); and The Skaggs Institute for Chemical Biology and Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California (D.O., B.F.C.).
Scripps Research Institute · USVirginia Commonwealth University · US
Funding
VCU Center for Drug Addiction ResearchP30DA033934 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Matthew Sean Halquist · 2014 to 2026
$13.8MSYNTHESIS OF SR141716A AND ANANDAMIDE ANALOGSP01DA009789 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI LICHTMAN, ARON H · 1995 to 2013
$11.6MSTRUCTURAL STUDIES OF FAAHP01DA017259 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI STEVENS, RAYMOND C · 2004 to 2013
$10.6MCHEMOPROTEOMIC METHODS FOR SERINE HYDROLASE INHIBITOR DEVELOPMENTR01DA033760 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI CRAVATT, BENJAMIN F, SCAMPAVIA, LOUIS DANIEL · 2012 to 2021
$5.1MMonoacylglycerol Lipase Inhibitors for Treating Opioid Use Disorders (RO)R01DA032933 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI CRAVATT, BENJAMIN F, LICHTMAN, ARON H · 2012 to 2014
$1.5MFunctional Characterization of Diacylglycerol Lipases in Mammalian PhysiologyR00DA035864 · NIDA · UNIVERSITY OF VIRGINIA · PI HSU, KU-LUNG · 2015 to 2017
$744kInhibiting peripheral diacylglycerol lipase beta - a novel target for pain reliefF32DA038493 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI WILKERSON, JENNY · 2015 to 2017
$157kFunctional Characterization of Diacylglycerol Lipases in Mammalian PhysiologyK99DA035864 · NIDA · SCRIPPS RESEARCH INSTITUTE, THE · PI HSU, KU-LUNG · 2014 to 2014
$128kNIDA NIH HHS F32 DA038493NIDA NIH HHS K99 DA035864NIDA NIH HHS P01 DA009789NIDA NIH HHS P01 DA017259NIDA NIH HHS P30 DA033934NIDA NIH HHS R00 DA035864NIDA NIH HHS R01 DA032933NIDA NIH HHS R01 DA033760
Abstract
Diacylglycerol lipase (DAGL)
Indexed as
AnalgesicsAnimalsBody TemperatureBrainDrug ToleranceEndocannabinoidsHyperalgesiaInflammationLipopolysaccharidesLipoprotein LipaseMaleMice, Inbred C57BLMice, Inbred ICRMice, KnockoutMotor ActivityNociceptionAnalgesicsdiacylglycerol lipase beta, mouseEndocannabinoidsLipopolysaccharidesLipoprotein LipaseThiazolesUrea
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.