Evidence map›Paper›PMID 28970356›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2018

Effects of meal ingestion on intramyocellular ceramide concentrations and fractional de novo synthesis in humans.

Jin Ook Chung, Christina Koutsari, Agnieszka Urszula Blachnio-Zabielska, Kazanna C Hames, Michael D Jensen

Erratum issuedOpen access · greenAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Trial
  2. Lipid metabolism in MASLD and MASH: From mechanism to the clinic.JHEP reports : innovation in hepatology · 2024
    Review
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Jin Ook ChungEndocrine Research Unit, Mayo Clinic , Rochester, Minnesota.
Christina KoutsariEndocrine Research Unit, Mayo Clinic , Rochester, Minnesota.
Agnieszka Urszula Blachnio-ZabielskaDepartment of Hygiene, Epidemiology and Metabolic Disorders, Medical University of Bialystok , Bialystok , Poland.
Kazanna C HamesEndocrine Research Unit, Mayo Clinic , Rochester, Minnesota.
Michael D JensenEndocrine Research Unit, Mayo Clinic , Rochester, Minnesota.ORCID 0000-0001-5589-8389
Mayo Clinic in Florida · USMedical University of Białystok · PL

Funding

MAYO CLINIC CENTER FOR TRANSLATIONAL SCIENCE ACTIVITIESUL1RR024150 · NCRR · MAYO CLINIC ROCHESTER · PI RIZZA, ROBERT A. · 2006 to 2011
$66.4M
Obesity and Energy Metabolism CoreP30DK050456 · NIDDK · UNIVERSITY OF MINNESOTA TWIN CITIES · PI BERNLOHR, DAVID A · 1995 to 2015
$17.0M
REGIONAL FATTY ACID METABOLISM IN HUMANSR01DK045343 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1992 to 2026
$12.9M
DIABETES AND METABOLISMT32DK007352 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1986 to 2026
$9.4M
FFA METABOLISM IN DIFFERENT TYPES OF HUMAN OBESITYR01DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI MICHAEL D. JENSEN · 1993 to 2026
$8.2M
Free Fatty Acid Metabolism in Different Types of Human ObesityR37DK040484 · NIDDK · MAYO CLINIC ROCHESTER · PI JENSEN, MICHAEL D. · 2003 to 2012
$4.1M
NCRR NIH HHS UL1 RR024150NIDDK NIH HHS P30 DK050456NIDDK NIH HHS R01 DK040484NIDDK NIH HHS R01 DK045343NIDDK NIH HHS R37 DK040484NIDDK NIH HHS T32 DK007352
6 · The paper itself

Abstract

We investigated the effects of meal ingestion on intramyofibrillar (IMF) and subsarcolemmal (SS) ceramide metabolism in volunteers ranging from lean to obese. Thirty-eight women and men underwent a steady-state meal ingestion protocol that included a 6.5-h infusion of [U-

Indexed as

AdultBiopsyBody CompositionCeramidesChemical FractionationEatingFemaleHumansLipid MetabolismMaleMealsMuscle Fibers, SkeletalMuscle, SkeletalObesityYoung AdultCeramidesinsulin resistanceisotopic tracersmealsobesityskeletal muscle

Identifiers

PMID28970356
PMCPMC5866415
OpenAlexW2760694393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.