ArticleInternational journal of cardiology2017
A novel method for evaluating regional RV function in the adult congenital heart with low-dose CT and SQUEEZ processing.
Article in International journal of cardiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 24 citations in OpenAlex.
- Deep learning enables fully automated cineCT-based assessment of regional right ventricular function.European heart journal. Imaging methods and practice · 2026Article
- Low dose threshold for measuring cardiac functional metrics using four-dimensional CT with deep learning.Journal of applied clinical medical physics · 2025Article
- Successful cardiac resynchronization therapy reduces negative septal work in patient-specific models of dyssynchronous heart failure.PLoS computational biology · 2024Article
- 3D regional evaluation of right ventricular myocardial work from cineCT.medRxiv : the preprint server for health sciences · 2024Article
- Successful Cardiac Resynchronization Therapy Reduces Negative Septal Work in Patient-Specific Models of Dyssynchronous Heart Failure.bioRxiv : the preprint server for biology · 2024Article
- Myocardial Regional Shortening from 4D Cardiac CT Angiography for the Detection of Left Ventricular Segmental Wall Motion Abnormality.Radiology. Cardiothoracic imaging · 2023Article
- Regional left ventricular endocardial strains estimated from low-dose 4DCT: Comparison with cardiac magnetic resonance feature tracking.Medical physics · 2022Article
- Right Ventricular and Pulmonary Computed Tomography Assessments in Paradoxical Low-Flow Low-Gradient Aortic Stenosis Undergoing Transcatheter Aortic Valve Replacement.Structural heart : the journal of the Heart Team · 2022Article
- Deep learning automates detection of wall motion abnormalitiesFrontiers in cardiovascular medicine · 2022Article
- Octree Representation Improves Data Fidelity of Cardiac CT Images and Convolutional Neural Network Semantic Segmentation of Left Atrial and Ventricular Chambers.Radiology. Artificial intelligence · 2021Article
- Automated cardiac volume assessment and cardiac long- and short-axis imaging plane prediction from electrocardiogram-gated computed tomography volumes enabled by deep learning.European heart journal. Digital health · 2021Article
- Anthropomorphic left ventricular mesh phantom: a framework to investigate the accuracy of SQUEEZ using Coherent Point Drift for the detection of regional wall motion abnormalities.Journal of medical imaging (Bellingham, Wash.) · 2019Article
- Regional myocardial strain measurements from 4DCT in patients with normal LV function.Journal of cardiovascular computed tomographyArticle
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5 authors at 2 institutions in 1 country.
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Abstract
backgroundMeasuring local RV function in adult congenital heart disease (ACHD) with echocardiography or MRI is challenging because of the complex geometry and existing pacing devices. Visual assessment of ventricular function via low-dose cardiac CT has been recently performed. This pilot study assessed whether low-dose 4D cine CT combined with automatic measurement of regional shortening could quantify right-ventricular function in ACHD patients.
methodsSeven patients with Tetralogy of Fallot either contraindicated for MRI or assessed for coronary artery disease and seven non-congenital patients were imaged with ECG-gated cardiac CT utilizing a 320-detector row scanner. Right ventricular global function and regional shortening were quantified.
resultsNon-congenital patients were imaged with 2.9±2.1mSv and 395±359 HU blood-myocardium contrast. The ACHD patients were imaged with 2.1±1.3mSv and 726±296 HU contrast. Right ventricles of the ACHD patients had higher end-diastolic volume (297±107mL vs 123±34mL, p=0.001), lower ejection fraction (32.0±4.9% vs 45.0±6.0%, p=0.001), and higher dyskinetic fraction (10.9±3.7% vs 2.6±2.8%, p<0.001) relative to the non-congenital controls.
conclusionsIn this initial pilot study, right ventricular global and regional systolic function were measured using low-dose cine CT with SQUEEZ quantification in non-congenital patients as well as ACHD patients with Tetralogy of Fallot. Unique regional features of RV dyskinesia were identified in the ACHD patients which could yield a more precise quantification of RV function.
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