Evidence map›Paper›PMID 28969863›Full record

ArticleJournal of the American Academy of Dermatology2018

Results of the 2016 International Skin Imaging Collaboration International Symposium on Biomedical Imaging challenge: Comparison of the accuracy of computer algorithms to dermatologists for the diagnosis of melanoma from dermoscopic images.

Michael A Marchetti, Noel C F Codella, Stephen W Dusza, David A Gutman, Brian Helba, Aadi Kalloo, Nabin Mishra, Cristina Carrera, M Emre Celebi, Jennifer L DeFazio and 7 more

Open access · bronzeAbstract readComparative Study
In one paragraph

Article in Journal of the American Academy of Dermatology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
101citing papers in PubMed, 5 pooled it
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

101 citing papers in PubMed, 5 syntheses or guidelines pooled it, 321 citations in OpenAlex.

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41 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 3 countries.

Michael A MarchettiDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Noel C F CodellaIBM Research Division, Thomas J. Watson Research Center, Yorktown Heights, New York.
Stephen W DuszaDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
David A GutmanDepartments of Neurology, Psychiatry, and Biomedical Informatics, Emory University School of Medicine, Atlanta, Georgia.
Brian HelbaKitware Inc, Clifton Park, New York.
Aadi KallooDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Nabin MishraStoecker & Associates, Rolla, Missouri.
Cristina CarreraMelanoma Unit, Department of Dermatology, Hospital Clinic, Institut d'Investigacions Biomèdiques August Pi i Sunyer, CIBER de Enfermedades Raras, Instituto de Salud Carlos III, University of Barcelona, Barcelona, Spain.
M Emre CelebiDepartment of Computer Science, University of Central Arkansas, Conway, Arkansas.
Jennifer L DeFazioDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Natalia JaimesDermatology Service, Aurora Centro Especializado en Cáncer de Piel, Medellín, Colombia; Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida.
Ashfaq A MarghoobDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Elizabeth QuigleyDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Alon ScopeDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Dermatology, Sheba Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Oriol YélamosDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York.
Allan C HalpernDermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address: halperna@mskcc.org.
International Skin Imaging Collaboration
Memorial Sloan Kettering Cancer Center · USConway School of Landscape Design · USEmory University · USIBM Research - Thomas J. Watson Research Center · USSheba Medical Center · ILUniversitat de Barcelona · ESUniversity of Miami · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundComputer vision may aid in melanoma detection.

objectiveWe sought to compare melanoma diagnostic accuracy of computer algorithms to dermatologists using dermoscopic images.

methodsWe conducted a cross-sectional study using 100 randomly selected dermoscopic images (50 melanomas, 44 nevi, and 6 lentigines) from an international computer vision melanoma challenge dataset (n = 379), along with individual algorithm results from 25 teams. We used 5 methods (nonlearned and machine learning) to combine individual automated predictions into "fusion" algorithms. In a companion study, 8 dermatologists classified the lesions in the 100 images as either benign or malignant.

resultsThe average sensitivity and specificity of dermatologists in classification was 82% and 59%. At 82% sensitivity, dermatologist specificity was similar to the top challenge algorithm (59% vs. 62%, P = .68) but lower than the best-performing fusion algorithm (59% vs. 76%, P = .02). Receiver operating characteristic area of the top fusion algorithm was greater than the mean receiver operating characteristic area of dermatologists (0.86 vs. 0.71, P = .001). LIMITATIONS: The dataset lacked the full spectrum of skin lesions encountered in clinical practice, particularly banal lesions. Readers and algorithms were not provided clinical data (eg, age or lesion history/symptoms). Results obtained using our study design cannot be extrapolated to clinical practice.

conclusionDeep learning computer vision systems classified melanoma dermoscopy images with accuracy that exceeded some but not all dermatologists.

Indexed as

AlgorithmsDermatologistsDermoscopyCongresses as TopicCross-Sectional StudiesDiagnosis, Computer-AssistedHumansLentigoMachine LearningMelanomaNevusROC CurveSkin Neoplasmscomputer algorithmcomputer visiondermatologistInternational Skin Imaging CollaborationInternational Symposium on Biomedical Imagingmachine learningmelanomareader studyskin cancer

Identifiers

PMID28969863
PMCPMC5768444
OpenAlexW2757940437

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.