Evidence map›Paper›PMID 28969611›Full record

Trial reportBMC cancer2017

TrueNTH sexual recovery study protocol: a multi-institutional collaborative approach to developing and testing a web-based intervention for couples coping with the side-effects of prostate cancer treatment in a randomized controlled trial.

D Wittmann, A Mehta, L Northouse, R Dunn, T Braun, A Duby, L An, L Arab, R Bangs, S Bober and 18 more

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC cancer, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02702453 (True NTH Sexual Recovery Intervention for Prostate Cancer Survivors and Their Partners), which is not on this map. Cited by 15 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 3 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02702453 nacompletednot on this map

True NTH Sexual Recovery Intervention for Prostate Cancer Survivors and Their Partners

TypeinterventionalSponsorUniversity of MichiganRan2016 to 2019Enrolled251ConditionsSexual Disfunction, Prostate CancerArmswebsite
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 22 citations in OpenAlex.

  1. African-American survivors of prostate cancer: a meta-synthesis of qualitative studies.Journal of cancer survivorship : research and practice · 2021
    Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. An online Sexual Health and Rehabilitation eClinic (TrueNTH SHAReClinic) for prostate cancer patients: a feasibility study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 15 institutions in 2 countries.

D WittmannUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA. dwittman@med.umich.edu.
A MehtaEmory University, Atlanta, GA, USA.
L NorthouseUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
R DunnUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
T BraunUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
A DubyUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
L AnUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
L ArabUniversity of California-Los Angeles, California, Los Angeles, USA.
R BangsUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
S BoberDana Farber Cancer Center and Harvard University, Boston, MA, USA.
J BrandonUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
M CowardUniversity of North Carolina, Chapel Hill, NC, USA.
M DunnUniversity of North Carolina, Chapel Hill, NC, USA.
M GalbraithUniversity of Colorado-Denver, Denver, CO, USA.
M GarciaUniversity of California-San Francisco, San Francisco, CA, USA.
J GiblinEmory University, Atlanta, GA, USA.
M GlodeUniversity of Colorado-Denver, Denver, CO, USA.
B KoontzDuke University, Durham, NC, USA.
A LoweProstate Cancer Foundation-Australia, St Leonards, Australia.
S MitchellUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
J MulhallMemorial Sloan Kettering Cancer Center, New York City, NY, USA.
C NelsonMemorial Sloan Kettering Cancer Center, New York City, NY, USA.
K PaichTrueNTH Movember Foundation, Michigan, USA.
C SaigalUniversity of California-Los Angeles, California, Los Angeles, USA.
T SkolarusUniversity of Michigan, 2800 Plymouth Road, Bldg. 16, Rm 110E, Ann Arbor, MI, 48109-2800, USA.
J StanfordFred Hutchinson Comprehensive Cancer Center, Seattle, Washington, USA.
T WalshUniversity of Washington, Seattle, Washington, USA.
C E PollackJohns Hopkins University, Baltimore, MD, USA.
University of Michigan–Ann Arbor · USEmory University · USMemorial Sloan Kettering Cancer Center · USUniversity of California, Los Angeles · USUniversity of North Carolina at Chapel Hill · USUniversity of Washington · USDuke University · USHarvard University · USJohns Hopkins University · USMovember · USProstate Cancer Foundation of Australia · AUUniversity of California, San Francisco · USUniversity of Colorado Denver · USUniversity of Denver · USVA Ann Arbor Healthcare System · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Improving the prostate cancer survivorship care of veteransIK2HX001162 · VA · VETERANS HEALTH ADMINISTRATION · PI SKOLARUS, TED ALBERT · 2015 to 2018
–
HSRD VA IK2 HX001162NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

backgroundOver half of men who receive treatment for prostate suffer from a range of sexual problems that affect negatively their sexual health, sexual intimacy with their partners and their quality of life. In clinical practice, however, care for the sexual side effects of treatment is often suboptimal or unavailable. The goal of the current study is to test a web-based intervention to support the recovery of sexual intimacy of prostate cancer survivors and their partners after treatment.

methodsThe study team developed an interactive, web-based intervention, tailored to type of treatment received, relationship status (partnered/non-partnered) and sexual orientation. It consists of 10 modules, six follow the trajectory of the illness and four are theme based. They address sexual side effects, rehabilitation, psychological impacts and coaching for self-efficacy. Each includes a video to engage participants, psychoeducation and activities completed by participants on the web. Tailored strategies for identified concerns are sent by email after each module. Six of these modules will be tested in a randomized controlled trial and compared to usual care. Men with localized prostate cancer with partners will be recruited from five academic medical centers. These couples (N = 140) will be assessed prior to treatment, then 3 months and 6 months after treatment. The primary outcome will be the survivors' and partners' Global Satisfaction with Sex Life, assessed by a Patient Reported Outcome Measure Information Systems (PROMIS) measure. Secondary outcomes will include interest in sex, sexual activity, use of sexual aids, dyadic coping, knowledge about sexual recovery, grief about the loss of sexual function, and quality of life. The impact of the intervention on the couple will be assessed using the Actor-Partner Interaction Model, a mixed-effects linear regression model able to estimate both the association of partner characteristics with partner and patient outcomes and the association of patient characteristics with both outcomes. DISCUSSION: The web-based tool represents a novel approach to addressing the sexual health needs of prostate cancer survivors and their partners that-if found efficacious-will improve access to much needed specialty care in prostate cancer survivorship.

trial registrationClinicaltrials.gov registration # NCT02702453 , registered on March 3, 2016.

Indexed as

Stress, PsychologicalAdolescentAdultFemaleHumansInternetMaleMiddle AgedProstatic NeoplasmsQuality of LifeSexual BehaviorSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalSexual PartnersSpousesYoung AdultProstate cancer sexual recovery cancer survivorship intervention

Identifiers

PMID28969611
PMCPMC5625773
OpenAlexW2758672909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.