Evidence map›Paper›PMID 28969439›Full record

Trial reportThe American journal of psychiatry2018

Improving the Efficiency of Psychotherapy for Depression: Computer-Assisted Versus Standard CBT.

Michael E Thase, Jesse H Wright, Tracy D Eells, Marna S Barrett, Stephen R Wisniewski, G K Balasubramani, Paul McCrone, Gregory K Brown

Registry-linked trialOpen access · bronzeAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The American journal of psychiatry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07163013 (Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms（CADS-D )), which is not on this map. Cited by 66 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed, 6 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07163013 narecruitingnot on this mapstarted 2025, after this paper: background citation

Digital Cognitive Behavioral Therapy for Chinese Adolescents With Depressive Symptoms（CADS-D ): A Randomized Clinical Trial

TypeinterventionalSponsorFirst Affiliated Hospital of Chongqing Medical UniversityRan2025 to 2026Enrolled200ConditionsDepressive SymptomArmsDigital cognitive behavioral therapy(DCBT), Regular mental health curriculum
3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 6 syntheses or guidelines pooled it, 138 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Guideline
  4. Therapist-guided remote versus in-person cognitive behavioural therapy: a systematic review and meta-analysis of randomized controlled trials.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2024
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Trial
  16. Trial
  17. Trial
  18. Article
  19. Review
  20. Article

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Michael E ThaseFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Jesse H WrightFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Tracy D EellsFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Marna S BarrettFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Stephen R WisniewskiFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
G K BalasubramaniFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Paul McCroneFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
Gregory K BrownFrom the Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia; the Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia; the Department of Psychiatry and Behavioral Sciences, University of Louisville, Louisville; the Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh; and King's Health Economics, Institute of Psychiatry, Psychology, and Neuroscience, King's College London.
University of Pennsylvania · US

Funding

1/2-Efficacy of Computer-Assisted Cognitive Behavior Therapy for DepressionR01MH082794 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI THASE, MICHAEL E · 2010 to 2013
$1.9M
2/2-Computer-Assisted Cognitive-Behavior Therapy for DepressionR01MH082762 · NIMH · UNIVERSITY OF LOUISVILLE · PI WRIGHT, JESSE H. · 2010 to 2013
$1.1M
NIMH NIH HHS R01 MH082762NIMH NIH HHS R01 MH082794
6 · The paper itself

Abstract

objectiveThe authors evaluated the efficacy and durability of a therapist-supported method for computer-assisted cognitive-behavioral therapy (CCBT) in comparison to standard cognitive-behavioral therapy (CBT).

methodA total of 154 medication-free patients with major depressive disorder seeking treatment at two university clinics were randomly assigned to either 16 weeks of standard CBT (up to 20 sessions of 50 minutes each) or CCBT using the "Good Days Ahead" program. The amount of therapist time in CCBT was planned to be about one-third that in CBT. Outcomes were assessed by independent raters and self-report at baseline, at weeks 8 and 16, and at posttreatment months 3 and 6. The primary test of efficacy was noninferiority on the Hamilton Depression Rating Scale at week 16.

resultsApproximately 80% of the participants completed the 16-week protocol (79% in the CBT group and 82% in the CCBT group). CCBT met a priori criteria for noninferiority to conventional CBT at week 16. The groups did not differ significantly on any measure of psychopathology. Remission rates were similar for the two groups (intent-to-treat rates, 41.6% for the CBT group and 42.9% for the CCBT group). Both groups maintained improvements throughout the follow-up.

conclusionsThe study findings indicate that a method of CCBT that blends Internet-delivered skill-building modules with about 5 hours of therapeutic contact was noninferior to a conventional course of CBT that provided over 8 additional hours of therapist contact. Future studies should focus on dissemination and optimizing therapist support methods to maximize the public health significance of CCBT.

Indexed as

Therapy, Computer-AssistedCognitive Behavioral TherapyFemaleHumansMajor Depressive DisorderMaleMiddle AgedPsychiatric Status Rating ScalesCognitive TherapyComputer-Assisted TherapyMood Disorders-DepressionPsychotherapy

Identifiers

PMID28969439
PMCPMC5848497
OpenAlexW2760933138

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.