Evidence map›Paper›PMID 28969126›Full record

ArticleJournal of clinical and diagnostic research : JCDR2017

Hepatitis B Core Antibody Negativity in a Chronic Hepatitis B Infected Patient: Report of an Unusual Serological Pattern.

Vijeta Bajpai, Ekta Gupta, Naveen Kundu, Shvetank Sharma, S M Shashtry

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of clinical and diagnostic research : JCDR, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Vijeta BajpaiSenior Resident, Department of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi, India.
Ekta GuptaAdditional Professor, Department of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi, India.
Naveen KunduSenior Resident, Department of Clinical Virology, Institute of Liver and Biliary Sciences, New Delhi, India.
Shvetank SharmaAssistant Professor, Department of Clinical Research, Institute of Liver and Biliary Sciences, New Delhi, India.
S M ShashtryAssistant Professor, Department of Hepatology, Institute of Liver and Biliary Sciences, New Delhi, India.
Institute of Liver and Biliary Sciences · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diagnosis of Hepatitis B Virus (HBV) infection is established by the presence of various hepatitis B serological and molecular markers. Expression of these serological markers may vary in natural course of HBV infection. We report a case of an unusual HBV serological pattern in a Chronic Hepatitis B (CHB) infected patient demonstrating absence of Hepatitis B core Antibody (Anti-HBc) in spite of presence of Hepatitis B surface Antigen (HBsAg) and HBV DNA. Since, anti-HBc represents a reliable serological marker for past exposure of HBV infection, therefore we emphasize on the presence of such unusual serological pattern which could lead to doubts in the interpretation of results.

Indexed as

Atypical serologyDiagnostic escapeHepatitis B core antigenHepatitis B virusImmunotolerance

Identifiers

PMID28969126
PMCPMC5620766
OpenAlexW2753236211

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.