Evidence map›Paper›PMID 28968953›Full record

ArticleOncotarget2017

Abderrahim Oussalah, Patrice Hodonou Avogbe, Erwan Guyot, Céline Chery, Rosa-Maria Guéant-Rodriguez, Nathalie Ganne-Carrié, Aurélie Cobat, Darius Moradpour, Bertrand Nalpas, Francesco Negro and 25 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncotarget, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. The repair geneOncology reviews · 2021
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 6 institutions in 4 countries.

Abderrahim Oussalah *INSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Patrice Hodonou Avogbe *INSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Erwan GuyotBiochemistry Unit, Jean Verdier Hospital, APHP, Bondy, France and University Paris 13-UFR SMBH/INSERM, Bobigny, France.
Céline CheryINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Rosa-Maria Guéant-RodriguezINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Nathalie Ganne-CarriéLiver Unit and Liver biobank CRB des Hôpitaux Universitaires Paris-Seine-Saint-Denis BB-0033-00027, Jean Verdier Hospital, APHP, Bondy, France.
Aurélie CobatLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Darius MoradpourDivision of Gastroenterology and Hepatology, University Hospital and University of Lausanne, Switzerland.
Bertrand NalpasDépartement d'Hépatologie, Hôpital Cochin (AP-HP), Université Paris Descartes, Paris, France.
Francesco NegroDivision of Clinical Pathology and Division of Gastroenterology and Hepatology, University Hospitals, Geneva, Switzerland.
Thierry PoynardUniversité Pierre et Marie Curie, Service d'Hépato-gastroentérologie, Hôpital Pitié-Salpêtrière (AP-HP), Paris, France.
Stanislas PolDépartement d'Hépatologie, Hôpital Cochin (AP-HP), Université Paris Descartes, Paris, France.
Pierre-Yves BochudInfectious Diseases Service, Department of Medicine, University Hospital and University of Lausanne, Switzerland.
Laurent AbelLaboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM U1163, Paris, France.
Hélène JeulinVirology Laboratory, Centre Hospitalier Universitaire de Nancy, Vandoeuvre-lès-Nancy, France.
Evelyne SchvoererVirology Laboratory, Centre Hospitalier Universitaire de Nancy, Vandoeuvre-lès-Nancy, France.
Nicodème ChabiLaboratory of Biochemistry and Molecular Biology, University of Cotonou, Cotonou, Benin.
Emile AmouzouLaboratory of Biochemistry and Nutrition, Lomé, University of Kara, Togo.
Ambaliou SanniLaboratory of Biochemistry and Molecular Biology, University of Cotonou, Cotonou, Benin.
Hélène BarraudDepartment of Hepato-Gastroenterology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France.
Pierre RouyerINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Thomas JosseDepartment of Molecular Medicine and Personalized Therapeutics, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France.
Laetitia GoffinetINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Jean-Louis JouveINSERM, U866 and INSERM, CIE 01, University Hospital of Dijon, University of Burgundy, Dijon, France.
Anne MinelloINSERM, U866 and INSERM, CIE 01, University Hospital of Dijon, University of Burgundy, Dijon, France.
Claire Bonithon-KoppINSERM, U866 and INSERM, CIE 01, University Hospital of Dijon, University of Burgundy, Dijon, France.
Gérard ThiefinDepartment of Hepato-Gastroenterology, Reims University Hospital, Reims, France.
Vincent Di MartinoDepartment of Hepatology, University Hospital of Besançon, Besançon, France.
Michel DoffoëlDepartment of Hepato-Gastroenterology, University Hospital of Strasbourg, Strasbourg, France.
Carine RichouDepartment of Hepatology, University Hospital of Besançon, Besançon, France.
Jean-Jacques RaabRegional Hospital of Metz, Metz, France.
Patrick HillonINSERM, U866 and INSERM, CIE 01, University Hospital of Dijon, University of Burgundy, Dijon, France.
Jean-Pierre BronowickiINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
Jean-Louis GuéantINSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.
CiRCE Study Group
Inserm · FRCentre Hospitalier Universitaire de Besançon · FRCentre Hospitalier Régional et Universitaire de Nancy · FRUniversité Paris Cité · FRUniversity of Kara · TGSorbonne Université · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The molecular mechanisms of hepatocellular carcinoma (HCC) carcinogenesis are still not fully understood. DNA repair defects may influence HCC risk. The aim of the study was to look for potential genetic variants of DNA repair genes associated with HCC risk among patients with alcohol- or viral-induced liver disease. We performed four case-control studies on 2,006 European- (Derivation#1 and #2 studies) and African-ancestry (Validation#1 and #2 studies) patients originating from several cohorts in order to assess the association between genetic variants on DNA repair genes and HCC risk using a custom array encompassing 94 genes. In the Derivation#1 study, the

Indexed as

BRIP1DNA repair geneshepatitis B virushepatitis C virushepatocellular carcinoma

Identifiers

PMID28968953
PMCPMC5609885
OpenAlexW2509983670

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.