Evidence map›Paper›PMID 28968918›Full record

ArticleJournal of surgical oncology2018

Racial and ethnic disparities in a national cohort of ampullary cancer patients.

Ibrahim Nassour, Ali A Mokdad, Rebecca M Minter, Patricio M Polanco, Mathew M Augustine, John C Mansour, Matthew R Porembka, Sam C Wang

Abstract read
In one paragraph

Article in Journal of surgical oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  11. Article
  12. [Treatment of Ampullary Adenocarcinoma].The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2023
    Review
  13. Treatment Approach to Adenocarcinoma of the Ampulla of Vater.Current treatment options in oncology · 2021
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Ibrahim NassourDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.ORCID http://orcid.org/0000-0002-9845-1074
Ali A MokdadDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
Rebecca M MinterDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
Patricio M PolancoDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
Mathew M AugustineDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
John C MansourDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
Matthew R PorembkaDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.
Sam C WangDepartment of Surgery, The University of Texas Southwestern Medical Center, Dallas, Texas.

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
NCATS NIH HHS UL1 TR001105
6 · The paper itself

Abstract

BACKGROUND AND

objectivesRacial and ethnic variations have been described in the different malignancies, but no such data exists for ampullary cancer. The aim of this study was to present an updated report on the epidemiology, treatment patterns, and survival of a national cohort of ampullary cancer patients.

methodsPatients diagnosed with ampullary cancer between 2004 and 2014 were identified in the National Cancer Database. Overall survival was estimated and compared between racial/ethnic groups using the log-rank test.

resultsA total of 14 879 patients were identified; 78% of the patients were White, 9% Hispanic, 8% Black, and 5% Asian. We noted significant differences in disease presentation, socioeconomic status, and outcomes. Blacks had the lowest median overall survival at 18.9 months followed by Whites at 23.9 months, Hispanics at 32.7 months, and Asians at 37.4 months. On a multivariate Cox proportional-hazards model, being Black was associated with worse survival compared to being White while being Asian and Hispanic were associated with better survival.

conclusionsOverall survival of ampullary cancer patients was independently associated with race and ethnicity. Further studies are needed to clarify whether these disparities are primarily due to socioeconomic status or biologic factors.

Indexed as

AgedAmpulla of VaterCombined Modality TherapyCommon Bile Duct NeoplasmsEthnicityFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRetrospective StudiesSEER ProgramSocioeconomic FactorsSurvival Rateampullary cancerampullary carcinomadisparityethnicityrace

Identifiers

PMID28968918
PMCPMC5826823

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.