Evidence map›Paper›PMID 28968784›Full record

ArticleBriefings in bioinformatics2019

MicroScope-an integrated resource for community expertise of gene functions and comparative analysis of microbial genomic and metabolic data.

Claudine Médigue, Alexandra Calteau, Stéphane Cruveiller, Mathieu Gachet, Guillaume Gautreau, Adrien Josso, Aurélie Lajus, Jordan Langlois, Hugo Pereira, Rémi Planel and 4 more

Abstract read
In one paragraph

Article in Briefings in bioinformatics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed.

  1. Traits analysis of an aphid-killingFrontiers in insect science · 2026
    Article
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  6. Article
  7. Review
  8. Dissemination of IncI plasmid encodingAntimicrobial agents and chemotherapy · 2023
    Article
  9. Review
  10. A roadmap for the functional annotation of protein families: a community perspective.Database : the journal of biological databases and curation · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Complete Genome Sequence ofMicrobiology resource announcements · 2020
    Article
  17. Article
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  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Claudine Médigue
Alexandra Calteau
Stéphane Cruveiller
Mathieu Gachet
Guillaume Gautreau
Adrien Josso
Aurélie Lajus
Jordan Langlois
Hugo Pereira
Rémi Planel
David Roche
Johan Rollin
Zoe Rouy
David Vallenet

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overwhelming list of new bacterial genomes becoming available on a daily basis makes accurate genome annotation an essential step that ultimately determines the relevance of thousands of genomes stored in public databanks. The MicroScope platform (http://www.genoscope.cns.fr/agc/microscope) is an integrative resource that supports systematic and efficient revision of microbial genome annotation, data management and comparative analysis. Starting from the results of our syntactic, functional and relational annotation pipelines, MicroScope provides an integrated environment for the expert annotation and comparative analysis of prokaryotic genomes. It combines tools and graphical interfaces to analyze genomes and to perform the manual curation of gene function in a comparative genomics and metabolic context. In this article, we describe the free-of-charge MicroScope services for the annotation and analysis of microbial (meta)genomes, transcriptomic and re-sequencing data. Then, the functionalities of the platform are presented in a way providing practical guidance and help to the nonspecialists in bioinformatics. Newly integrated analysis tools (i.e. prediction of virulence and resistance genes in bacterial genomes) and original method recently developed (the pan-genome graph representation) are also described. Integrated environments such as MicroScope clearly contribute, through the user community, to help maintaining accurate resources.

Indexed as

Genome, MicrobialSoftwareComputational BiologyComputer GraphicsDatabase Management SystemsDatabases, ChemicalGenomicsInternetMetabolic Networks and PathwaysMicrobiological PhenomenaMolecular Sequence AnnotationUser-Computer Interfacecomparative genomicsgene function curationmetabolic networksmicrobial genome annotation systemtranscriptomicsvariant detection

Identifiers

PMID28968784
PMCPMC6931091

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.