Evidence map›Paper›PMID 28968731›Full record

ArticleThe Journal of infectious diseases2017

Estimating HPV DNA Deposition Between Sexual Partners Using HPV Concordance, Y Chromosome DNA Detection, and Self-reported Sexual Behaviors.

Talía Malagón, Ann N Burchell, Mariam El-Zein, Julie Guénoun, Pierre-Paul Tellier, François Coutlée, Eduardo L Franco, HITCH Study Group

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of infectious diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Epidemiology of genital human papillomavirus infections in sequential male sex partners of young females.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2024
    Article
  7. Article
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Article
  13. Vaccination of Young Women Decreases Human Papillomavirus Transmission in Heterosexual Couples: Findings from the HITCH Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Talía MalagónDivision of Cancer Epidemiology, Department of Oncology, McGill University, Montreal, Canada.
Ann N BurchellDepartment of Family and Community Medicine and Centre for Urban Health Solutions, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto.
Mariam El-ZeinDivision of Cancer Epidemiology, Department of Oncology, McGill University, Montreal, Canada.
Julie GuénounDépartement de Microbiologie et Infectiologie, Centre Hospitalier de l'Université de Montréal.
Pierre-Paul TellierDepartment of Family Medicine, McGill University.
François CoutléeDépartement de Microbiologie et Infectiologie, Centre Hospitalier de l'Université de Montréal.
Eduardo L FrancoDivision of Cancer Epidemiology, Department of Oncology, McGill University, Montreal, Canada.
HITCH Study Group
Centre Hospitalier de l’Université de Montréal · CAMcGill University · CAUniversity of Toronto · CA

Funding

CIHR
6 · The paper itself

Abstract

Background: Detection of human papillomavirus (HPV) DNA in genital samples may not always represent true infections but may be depositions from infected sexual partners. We examined whether sexual risk factors and a biomarker (Y chromosome DNA) were associated with genital HPV partner concordance and estimated the fraction of HPV detections potentially attributable to partner deposition. Methods: The HITCH study enrolled young women attending a university or college in Montréal, Canada, and their male partners, from 2005 to 2010. We tested baseline genital samples for Y chromosome DNA and HPV DNA using polymerase chain reaction. Results: Type-specific HPV concordance was 42.4% in partnerships where at least one partner was HPV DNA positive. Y chromosome DNA predicted type-specific HPV concordance in univariate analyses, but in multivariable models the independent predictors of concordance were days since last vaginal sex (26.5% higher concordance 0-1 vs 8-14 days after last vaginal sex) and condom use (22.6% higher concordance in never vs always users). We estimated that 14.1% (95% confidence interval [CI], 6.3-21.9%) of HPV DNA detections in genital samples were attributable to vaginal sex in the past week. Conclusions: A substantial proportion of HPV DNA detections may be depositions due to recent unprotected vaginal sex.

Indexed as

Sexual BehaviorSexual PartnersAdolescentAdultAlphapapillomavirusBiomarkersCanadaChromosomes, Human, YDNA, ViralFemaleHumansMalePapillomavirus InfectionsPopulation SurveillancePrevalenceRisk FactorsBiomarkersDNA, Viralconcordancedepositionhuman papillomavirussexual behaviortransmission

Identifiers

PMID28968731
PMCPMC5853413
OpenAlexW2789831080

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.