Evidence map›Paper›PMID 28968151›Full record

ArticleDevelopmental neurorehabilitation2018

Cerebellar pilocytic astrocytoma in childhood: Investigating the long-term impact of surgery on cognitive performance and functional outcome.

Thomas Pletschko, Anna Felnhofer, Doris Lamplmair, Christian Dorfer, Thomas Czech, Monika Chocholous, Irene Slavc, Ulrike Leiss

Open access · hybridAbstract read
In one paragraph

Article in Developmental neurorehabilitation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. Pilocytic astrocytoma: A rare case report.Radiology case reports · 2025
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. NF-кB inhibition by DHMEQ: in vitro antiproliferative effects on pilocytic astrocytoma and concise review of the current literature.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2020
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Thomas Pletschkoa Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-7865-0164
Anna Felnhofera Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-0081-7489
Doris Lamplmaira Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.
Christian Dorferb Department of Neurosurgery , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-1843-7732
Thomas Czechb Department of Neurosurgery , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-7865-0164
Monika Chocholousa Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-3549-3330
Irene Slavca Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0002-9419-6790
Ulrike Leissa Department of Pediatrics and Adolescent Medicine , Medical University of Vienna , Wien , Austria.ORCID http://orcid.org/0000-0003-2605-8334
Medical University of Vienna · AT

Funding

Austrian Science Fund FWF KLI 252
6 · The paper itself

Abstract

objectivePrevious studies differ regarding the long-term effects of surgically removed pediatric cerebellar pilocytic astrocytomas (CPA). Thus, the aim of this study was to investigate the long-term impact on neurocognitive and functional outcome and to analyze age as an influencing factor.

methodsFourteen CPA patients were compared to the age norm and to a group of 14 high-achieving peers regarding cognitive functioning, health-related quality of life (HRQoL), and stress regulation. Mean follow-up time after diagnosis was 13.29 years (range: 3-21 years).

resultsPatients showed satisfactory academic achievement and did not differ from the norm except for the bodily dimension of HRQoL. However, there were marked differences in specific neurocognitive functions between patients and high achievers. Age at diagnosis did not influence neurocognitive outcome.

conclusionCPA patients treated with surgery only seem to have a favorable long-term outcome, yet, in comparison with high achievers specific cognitive impairments become apparent.

Indexed as

CognitionAdolescentAdultAstrocytomaCerebellar NeoplasmsChildChild, PreschoolCognition DisordersFemaleHumansMalePostoperative ComplicationsAcademic achievementcerebellar pilocytic astrocytomacognitive performancelong-term effectneuropsychologyposterior fossa tumor

Identifiers

PMID28968151
PMCPMC6050644
OpenAlexW2773302493

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.