Evidence map›Paper›PMID 28967546›Full record

SynthesisThe journal of allergy and clinical immunology. In practice

Overweight, Obesity, and Lung Function in Children and Adults-A Meta-analysis.

Erick Forno, Yueh-Ying Han, James Mullen, Juan C Celedón

Open access · greenAbstract readMeta-Analysis
In one paragraph

Synthesis in The journal of allergy and clinical immunology. In practice. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 3 pooled it
14.5field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 3 syntheses or guidelines pooled it, 271 citations in OpenAlex.

  1. Pooled it
  2. Differential gene expression in nasal airway epithelium from overweight or obese youth with asthma.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2022
    Pooled it
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  9. Prevalence of Overweight and Obesity and Their Impact on Lung Function in Healthy Bulgarian Children and Adolescents: A Cross-Sectional Study.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
    Article
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  17. Review
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84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Erick FornoDivision of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pa. Electronic address: erick.forno@chp.edu.
Yueh-Ying HanDivision of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pa.
James MullenCollege of Science, University of Notre Dame, Notre Dame, Ind.
Juan C CeledónDivision of Pulmonary Medicine, Allergy and Immunology, Department of Pediatrics, Children's Hospital of Pittsburgh of UPMC, University of Pittsburgh, Pittsburgh, Pa.
University of Pittsburgh · USUniversity of Notre Dame · US

Funding

Epigenetic Variation and Childhood Asthma in Puerto RicansR01HL117191 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2013 to 2020
$5.8M
Genes, Home Allergens and Asthma Puerto Rican ChildrenR01HL079966 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2006 to 2010
$3.8M
Vitamin D to Prevent Severe Asthma Exacerbations in High-Risk Children - CCCU01HL119952 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CELEDON, JUAN CARLOS · 2015 to 2018
$2.9M
Obesity and Asthma Subphenotypes and Underlying Genetic and Genomic PathwaysK08HL125666 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FORNO, ERICK · 2015 to 2018
$589k
NHLBI NIH HHS K08 HL125666NHLBI NIH HHS R01 HL079966NHLBI NIH HHS R01 HL117191NHLBI NIH HHS U01 HL119952
6 · The paper itself

Abstract

backgroundThere is conflicting evidence on the effect of obesity on lung function in adults and children with and without asthma. We aimed to evaluate the relation between overweight or obesity and lung function, and whether such relationship varies by age, sex, or asthma status.

methodsWe searched PubMed, Scopus, CINAHL, Cochrane, and EMBASE for all studies (in English) reporting on obesity status (by body mass index) and lung function, from 2005 to 2017. Main outcomes were forced expiratory volume in 1 second (FEV

resultsAll measures of lung function were decreased among obese subjects. Obese adults showed a pattern (lower FEV

conclusionsObesity is detrimental to lung function, but specific patterns differ between children and adults. Physicians should be aware of adverse effects of obesity on lung function, and weight control should be considered in the management of airway disease among the obese.

Indexed as

AdultAsthmaChildHumansLungObservational Studies as TopicOverweightRespiratory Function TestsAsthmaChildhood obesityLung functionMeta-analysisObesity

Identifiers

PMID28967546
PMCPMC5845780
OpenAlexW2759448078

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.