Evidence map›Paper›PMID 28967387›Full record

ArticleThe Journal of pediatrics2017

What Urinary Colony Count Indicates a Urinary Tract Infection in Children?

William Primack, Timothy Bukowski, Richard Sutherland, Lisa Gravens-Mueller, Myra Carpenter

Registry-linked trialAbstract read
In one paragraph

Article in The Journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00405704 (Randomized Intervention for Children With Vesicoureteral Reflux), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00405704 phase3completednot on this map

Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)

TypeinterventionalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran2007 to 2014Enrolled607ConditionsVesicoureteral Reflux, Urinary Tract InfectionsArmsTrimethoprim-Sulfamethoxazole, Placebo
3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

William PrimackUniversity of North Carolina, Chapel Hill, NC. Electronic address: wprimack@med.unc.edu.
Timothy BukowskiUniversity of North Carolina, Chapel Hill, NC.
Richard SutherlandUniversity of North Carolina, Chapel Hill, NC.
Lisa Gravens-MuellerUniversity of North Carolina, Chapel Hill, NC.
Myra CarpenterUniversity of North Carolina, Chapel Hill, NC.

Funding

Randomized Intervention for Vesicoureteral Reflux (RIVUR)U01DK074059 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARPENTER, MYRA A. · 2005 to 2012
$11.3M
POET Study: Clinical Trial of Girls with RefluxU01DK074063 · NIDDK · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI GREENFIELD, SAUL PHILIP · 2005 to 2012
$5.0M
RIVUR - Randomized Intervention for Children with Vesicoureteral RefluxU01DK074053 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOBERMAN, ALEJANDRO · 2005 to 2012
$4.3M
RIVUR StudyU01DK074062 · NIDDK · WAYNE STATE UNIVERSITY · PI MATTOO, TEJ K · 2005 to 2012
$4.0M
Randomized Intervention for VesicolUreteral Reflux (RIVUR) StudyU01DK074064 · NIDDK · CHILDREN'S HOSP OF PHILADELPHIA · PI KEREN, RON · 2005 to 2012
$2.8M
Randomized Intervention for Vesico-Ureteral Reflux (RIVUR) TrialU01DK074082 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI WANG, MING-HSIEN · 2005 to 2012
$2.5M
NIDDK NIH HHS U01 DK074053NIDDK NIH HHS U01 DK074059NIDDK NIH HHS U01 DK074062NIDDK NIH HHS U01 DK074063NIDDK NIH HHS U01 DK074064NIDDK NIH HHS U01 DK074082
6 · The paper itself

Abstract

Post-hoc analysis of the Randomized Intervention for Children with Vesicoureteral Reflux study suggests that, in concordance with European guidelines, using bacteriologic criterion of ≥10 000 colony forming units/mL of a single organism does not decrease diagnostic specificity of an urinary tract infection in children aged 2 months to 6 years in a properly collected urine if symptoms/fever and pyuria are present.

trial registrationClinicalTrials.gov: NCT00405704.

Indexed as

BacteriuriaChildChild, PreschoolColony Count, MicrobialFemaleFeverHumansInfantMalePyuriaReference StandardsUrinary Tract InfectionsUrineguidelinepyuriasuprapubic aspirationurinary catheterizationvesicoureteral reflux

Identifiers

PMID28967387
PMCPMC5705283

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.