Evidence map›Paper›PMID 28967230›Full record

ArticleLower urinary tract symptoms2019

Prevalence of overactive bladder in China, Taiwan and South Korea: Results from a cross-sectional, population-based study.

Yao-Chi Chuang, Shih-Ping Liu, Kyu-Sung Lee, Limin Liao, Jianye Wang, Tag Keun Yoo, Romeo Chu, Budiwan Sumarsono

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in Lower urinary tract symptoms, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04420533 (Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study), which is not on this map. Cited by 74 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 7 pooled it
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04420533 nacompletednot on this mapstarted 2020, after this paper: background citation

Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron 50mg in Sexually Active Men With Bothersome Overactive Bladder Symptoms - A Multicenter, Randomized Study

TypeinterventionalSponsorChang Gung Memorial HospitalRan2020 to 2022Enrolled150ConditionsUrinary Bladder, Overactive, Sexual Behavior, Sexual Activity, Behavior TherapyArmsBehavior therapy alone, Mirabegron 50 MG Extended Release Oral Tablet
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 7 syntheses or guidelines pooled it, 115 citations in OpenAlex.

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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Yao-Chi ChuangDepartment of Urology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
Shih-Ping LiuDepartment of Urology, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.
Kyu-Sung LeeDepartment of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.ORCID http://orcid.org/0000-0003-0891-2488
Limin LiaoDepartment of Urology, China Rehabilitation Research Center, Capital Medical University, Beijing, China.
Jianye WangDepartment of Urology, Beijing Hospital, Beijing, China.
Tag Keun YooDepartment of Urology, Nowon Eulji Medical Center, Eulji University School of Medicine, Seoul, Korea.
Romeo ChuAstellas Pharma Singapore Pte. Ltd, Singapore.
Budiwan SumarsonoAstellas Pharma Singapore Pte. Ltd, Singapore.
Astellas Pharma (Japan) · JPBeijing Hospital · CNCapital Medical University · CNChang Gung University · TWEulji University · KRNational Taiwan University Hospital · TWSamsung Medical Center · KR

Funding

Astellas Pharma Singapore Pte Ltd
6 · The paper itself

Abstract

objectiveThe aim of the present study was to determine the prevalence of overactive bladder (OAB) in individuals aged ≥40 years in China, Taiwan, and South Korea.

methodsThe present cross-sectional population-representative Internet-based study investigated OAB symptoms in men and women aged ≥40 years using the overactive bladder symptom score. Additional instruments included the International Index of Erectile Function (men only) and the Sexual Quality of Life - Female (women only) questionnaires, as well as Patient Perception of Bladder Condition (PPBC).

resultsIn all, 8284 individuals participated in the study. The prevalence of OAB was 20.8% overall (women 22.1%, men 19.5%) and increased significantly with age, from 10.8% in those aged 40-44 years to 27.9% in those aged >60 years (P = .001). The presence of comorbid conditions (e.g. neurological disease, diabetes) was associated with a significantly increased prevalence of OAB. Increasing symptom severity was associated with significantly worsening patient perception of bladder condition responses. Just under half (48%) of those with no OAB had no lower urinary tract symptoms (LUTS), whereas 88% of those with severe symptoms had all 3 LUTS (International Continence Society definition) symptom categories (voiding, post-micturition, and storage symptoms). Of those without OAB, 10% reported visiting healthcare professionals for urinary symptoms, compared with 64% of those with severe OAB symptoms (P = .001). Increased symptom severity was significantly associated with lower sexual quality of life in both men and women.

conclusionsOAB symptoms were found to affect 1 in 5 individuals aged ≥40 years in China, Taiwan, and South Korea, becoming more common with increasing age. The results suggest that many more individuals with OAB could benefit by consulting healthcare professionals.

Indexed as

AdultAgedChinaCross-Sectional StudiesFemaleHumansLower Urinary Tract SymptomsMaleMiddle AgedPrevalenceQuality of LifeRepublic of KoreaTaiwanUrinary Bladder, OveractiveChinaoveractive bladderprevalenceRepublic of KoreaTaiwan

Identifiers

PMID28967230
PMCPMC7379992
OpenAlexW2762309295

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.