Evidence map›Paper›PMID 28967122›Full record

ArticleBritish journal of pharmacology2017

Immuno-pharmacological characterization of group II metabotropic glutamate receptors controlling glutamate exocytosis in mouse cortex and spinal cord.

Guendalina Olivero, Tommaso Bonfiglio, Matteo Vergassola, Cesare Usai, Barbara Riozzi, Giuseppe Battaglia, Ferdinando Nicoletti, Anna Pittaluga

Open access · bronzeAbstract read
In one paragraph

Article in British journal of pharmacology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 20 citations in OpenAlex.

  1. Review
  2. Article
  3. Presynaptic 5-HTCells · 2022
    Article
  4. Advances in translating mGluPharmacology, biochemistry, and behavior · 2022
    Review
  5. Article
  6. Review
  7. Antibodies Against the NHFrontiers in immunology · 2021
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Guendalina OliveroDepartment of Pharmacy, DiFAR, University of Genoa, Genoa, Italy.
Tommaso BonfiglioDepartment of Pharmacy, DiFAR, University of Genoa, Genoa, Italy.
Matteo VergassolaDepartment of Pharmacy, DiFAR, University of Genoa, Genoa, Italy.
Cesare UsaiNational Research Council, Institute of Biophysics, Genoa, Italy.
Barbara RiozziI.R.C.C.S. Neuromed, Località Camerelle, Pozzilli, Italy.
Giuseppe BattagliaI.R.C.C.S. Neuromed, Località Camerelle, Pozzilli, Italy.
Ferdinando NicolettiI.R.C.C.S. Neuromed, Località Camerelle, Pozzilli, Italy.
Anna PittalugaDepartment of Pharmacy, DiFAR, University of Genoa, Genoa, Italy.ORCID http://orcid.org/0000-0002-4011-1165
University of Genoa · ITIstituto Neurologico Mediterraneo · ITNational Research Council · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeWe recently proposed the existence of mGlu EXPERIMENTAL APPROACH: We studied the effect of LY566332, an mGlu KEY

resultsCortical synaptosomes possess LY566332-sensitive autoreceptors that are slightly, although significantly, susceptible to LY2389575. In contrast, LY566332-insensitive and LY2389575-sensitive autoreceptors are present in spinal cord terminals. BINA and ML337 mimicked LY566332 and LY2389575, respectively, in controlling LY379268-mediated inhibition of glutamate exocytosis from both cortical and spinal cord synaptosomes. Incubation of cortical synaptosomes with anti-mGlu CONCLUSIONS AND IMPLICATIONS: We confirmed that mGlu

Indexed as

ExocytosisAnimalsGlutamic AcidMaleMiceMice, Inbred C57BLMice, KnockoutMotor CortexReceptors, Metabotropic GlutamateSpinal CordSynaptosomesGlutamic AcidReceptors, Metabotropic Glutamate

Identifiers

PMID28967122
PMCPMC5727332
OpenAlexW2758425482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.