ArticleeNeuro
Local or Not Local: Investigating the Nature of Striatal Theta Oscillations in Behaving Rats.
Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- A reversible rat model of hyposmia affects respiration-linked brain oscillations and behavior.iScience · 2026Article
- Acute effects of upper-limb blood flow restriction training on dual-task postural control and physiological correlates in older adults.Journal of neuroengineering and rehabilitation · 2026Article
- Optogenetic Mapping of Rhythmic Phase-Dependent Excitability in the Mouse Striatum.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Beta-frequency sensory stimulation enhances gait rhythmicity through strengthened coupling between striatal networks and stepping movement.Nature communications · 2024Article
- Differential effects of allopregnanolone and diazepam on social behavior through modulation of neural oscillation dynamics in basolateral amygdala and medial prefrontal cortex.Frontiers in cellular neuroscience · 2024Article
- Prelimbic cortex and nucleus accumbens core resting state signaling dynamics as a biomarker for cocaine seeking behaviors.Addiction neuroscience · 2023Article
- Site-dependent shaping of field potential waveforms.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Visual cortical LFP in relation to the hippocampal theta rhythm in track running rats.Frontiers in cellular neuroscience · 2023Article
- Theoretical considerations and supporting evidence for the primary role of source geometry on field potential amplitude and spatial extent.Frontiers in cellular neuroscience · 2023Review
- Cholinergic control of striatal GABAergic microcircuits.Cell reports · 2022Article
- Prefrontal and hippocampal theta rhythm show anxiolytic-like changes during periaqueductal-elicited "panic" in rats.Hippocampus · 2022Article
- Deep brain stimulation in the subthalamic nucleus for Parkinson's disease can restore dynamics of striatal networks.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Sharp Tuning of Head Direction and Angular Head Velocity Cells in the Somatosensory Cortex.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Neural Oscillations in Aversively Motivated Behavior.Frontiers in behavioral neuroscience · 2022Review
- Volitional control of individual neurons in the human brain.Brain : a journal of neurology · 2021Article
- Coupling between motor cortex and striatum increases during sleep over long-term skill learning.eLife · 2021Article
- Cross Laminar Traveling Components of Field Potentials due to Volume Conduction of Non-Traveling Neuronal Activity in Macaque Sensory Cortices.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021Article
- Differential dopaminergic modulation of spontaneous cortico-subthalamic activity in Parkinson's disease.eLife · 2021Article
- State Transitions During Discrimination Learning in the Gerbil Auditory Cortex Analyzed by Network Causality Metrics.Frontiers in systems neuroscience · 2021Article
- Interindividual differences in memory system local field potential activity predict behavioral strategy on a dual-solution T-maze.Hippocampus · 2020Article
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5 authors.
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Abstract
In the cortex and hippocampus, neuronal oscillations of different frequencies can be observed in local field potentials (LFPs). LFPs oscillations in the theta band (6-10 Hz) have also been observed in the dorsolateral striatum (DLS) of rodents, mostly during locomotion, and have been proposed to mediate behaviorally-relevant interactions between striatum and cortex (or between striatum and hippocampus). However, it is unclear if these theta oscillations are generated in the striatum. To address this issue, we recorded LFPs and spiking activity in the DLS of rats performing a running sequence on a motorized treadmill. We observed an increase in rhythmical activity of the LFP in the theta-band during run compared to rest periods. However, several observations suggest that these oscillations are mainly generated outside of the striatum. First, theta oscillations disappeared when LFPs were rereferenced against a striatal recording electrode and the imaginary coherence between LFPs recorded at different locations within the striatum was null. Second, 8% of the recorded neurons had their spiking activity phase-locked to the theta rhythm. Third, Granger causality analyses between LFPs simultaneously recorded in the cortex and the striatum revealed that the interdependence between these two signals in the theta range was mostly accounted for by a common external source. The most parsimonious interpretation of these results is that theta oscillations observed in striatal LFPs are largely contaminated by volume-conducted signals. We propose that striatal LFPs are not optimal proxies of network dynamics in the striatum and should be interpreted with caution.
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