Evidence map›Paper›PMID 28966952›Full record

ArticleTobacco regulatory science2017

Dual Use of Cigarettes, Little Cigars, Cigarillos, and Large Cigars: Smoking Topography and Toxicant Exposure.

Wallace B Pickworth, Zachary R Rosenberry, Kevin E O'Grady, Bartosz Koszowski

Abstract read
In one paragraph

Article in Tobacco regulatory science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Regulatory Approaches and Implementation of Minimally Addictive Combusted Products.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2022
    Pooled it
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Survey of Premium Versus Large Manufactured Cigars Use in U.S. Consumers.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Nicotine and Toxicant Exposure Among Concurrent Users (Co-Users) of Tobacco and Cannabis.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2020
    Article
  15. Article
  16. Article
  17. Biomarkers of Exposure among U.S. Adult Cigar Smokers: Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013-2014).Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Article
  18. Article
  19. A Survey of Nicotine Yields in Small Cigar Smoke: Influence of Cigar Design and Smoking Regimens.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2018
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Wallace B PickworthBattelle Public Health Center for Tobacco Research, Baltimore, MD.
Zachary R RosenberryBattelle Public Health Center for Tobacco Research, Baltimore, MD.
Kevin E O'GradyDepartment of Psychology, Universityof Maryland, College Park, MD.
Bartosz KoszowskiBattelle Public Health Center for Tobacco Research, Baltimore, MD.

Funding

Mainstream Smoke Composition and Toxin Exposure from Prototypical Cigar ProductsR01CA158045 · NCI · BATTELLE CENTERS/PUB HLTH RES & EVALUATN · PI PICKWORTH, WALLACE BRUCE · 2012 to 2014
$2.1M
Small Conference on Cigar Use: Epidemiology, Toxicant Exposure, and Smoking BehaviorR13FD005491 · FDA · BATTELLE CENTERS/PUB HLTH RES & EVALUATN · PI PICKWORTH, WALLACE BRUCE · 2016 to 2016
$49k
FDA HHS R13 FD005491NCI NIH HHS R01 CA158045
6 · The paper itself

Abstract

objectiveSmoking topography variables and toxicant exposure (plasma nicotine and exhaled CO) were examined in 3 groups of study participants that smoked both cigarettes and either filtered little cigars (Winchester), cigarillos (Black & Mild), or large cigars (Phillies Blunt).

methodsLaboratory ad lib smoking of the cigar products was collected with a smoking puff analyzer; plasma levels of nicotine and exhaled CO were collected before and after smoking.

resultsAlthough there were no statistically significant differences in demographic and cigarette smoking topography among the groups, there were significant differences in how the different cigar products were smoked. Plasma nicotine boost was similar after all products but exhaled CO was greater after the cigarillo and large cigar than the little cigar. Some of the differences were due to the differences in article size but other differences were apparent even after adjustment for the amount of tobacco burned or the mouth intake (puff volume).

conclusionsThe topography findings of differences among products challenge the practice of grouping cigars as a single entity in surveys, regulatory decisions, and discussions of toxicant exposure. The results add to the discussion of distinctions among products in the scientific assessment of public health risk and regulatory decisions.

Indexed as

cigarilloslarge cigarslittle cigarssmokingtobaccotopographytoxicant exposure

Identifiers

PMID28966952
PMCPMC5614467

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.