Evidence map›Paper›PMID 28966908›Full record

ArticleJournal of obsessive-compulsive and related disorders2017

The link between ADHD-like inattention and obsessions and compulsions during treatment of youth with OCD.

Andrew G Guzick, Joseph P H McNamara, Adam M Reid, Amanda M Balkhi, Eric A Storch, Tanya K Murphy, Wayne K Goodman, Regina Bussing, Gary R Geffken

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In one paragraph

Article in Journal of obsessive-compulsive and related disorders, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Andrew G GuzickUniversity of Florida, College of Medicine, 8491 NW 39th Avenue, Gainesville, Florida, 32606.
Joseph P H McNamaraUniversity of Florida, College of Medicine, 8491 NW 39th Avenue, Gainesville, Florida, 32606.
Adam M ReidChild and Adolescent OCD Institute, McLean Hospital, Harvard Medical School, 23 Isaac St, Middleborough, MA 02346.
Amanda M BalkhiUniversity of Florida, College of Medicine, 8491 NW 39th Avenue, Gainesville, Florida, 32606.
Eric A StorchDepartment of Pediatrics, University of South Florida, 880 6th Street South, Box 7523, St. Petersburg, FL 33701, USA.
Tanya K MurphyDepartment of Pediatrics, University of South Florida, 880 6th Street South, Box 7523, St. Petersburg, FL 33701, USA.
Wayne K GoodmanMenninger Department of Psychiatry, Baylor College of Medicine, 1977 Butler Blvd. Houston, TX 77030, USA.
Regina BussingUniversity of Florida, College of Medicine, 8491 NW 39th Avenue, Gainesville, Florida, 32606.
Gary R GeffkenThe Geffken Group, 2833 NW 41 St #140, Gainesville, FL 32606, USA.
University of Florida · USBaylor College of Medicine · USFlorida College · USHarvard University · USJohns Hopkins All Children's Hospital · USUniversity of South Florida · US

Funding

SSRI-Induced Activation Syndrome In Pediatric OCDU01MH078594 · NIMH · UNIVERSITY OF FLORIDA · PI BUSSING, REGINA · 2007 to 2010
$928k
NIMH NIH HHS U01 MH078594
6 · The paper itself

Abstract

Attention-deficit/hyperactivity disorder (ADHD) has been found to be highly comorbid in children and adolescents with obsessive-compulsive disorder (OCD). Some have proposed, however, that obsessive anxiety may cause inattention and executive dysfunction, leading to inappropriate ADHD diagnoses in those with OCD. If this were the case, these symptoms would be expected to decrease following successful OCD treatment. The present study tested this hypothesis and evaluated whether ADHD symptoms at baseline predicted OCD treatment response. Obsessive-compulsive and ADHD symptoms were assessed in 50 youth enrolled in a randomized controlled trial investigating selective serotonin reuptake inhibitor and cognitive behavioral treatment. Repeated-measures analysis of variance (RMANOVA) revealed that ADHD symptoms at baseline do not significantly predict treatment outcome. A multivariate RMANOVA found that OCD treatment response moderated change in inattention; participants who showed greater reduction in OCD severity experienced greater reduction in ADHD-inattentive symptoms, while those with less substantial reduction in obsessions and compulsions showed less change. These findings suggest that children and adolescents with OCD and inattention may experience meaningful improvements in attention problems following OCD treatment. Thus, in many youth with OCD, inattention may be inherently tied to obsessions and compulsions. Clinicians may consider addressing OCD in treatment before targeting inattentive-type ADHD.

Identifiers

PMID28966908
PMCPMC5619255
OpenAlexW2555206606

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.