Evidence map›Paper›PMID 28966902›Full record

ArticleCurrent treatment options in allergy2017

Mental Health in Allergic Rhinitis: Depression and Suicidal Behavior.

Ameya U Amritwar, Christopher A Lowry, Lisa A Brenner, Andrew J Hoisington, Robert Hamilton, John W Stiller, Teodor T Postolache

Open access · greenAbstract read
In one paragraph

Article in Current treatment options in allergy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 58 citations in OpenAlex.

  1. Nutrients · 2020
    Trial
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Impact of socioeconomic factors on allergic diseases.The Journal of allergy and clinical immunology · 2024
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Psychological impacts of coronavirus disease 2019 on people with asthma, allergic rhinitis, and food allergy.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2022
    Review
  15. Article
  16. Article
  17. Drug-induced Neuropsychiatric Adverse Events Using Post-Marketing Surveillance.Current reviews in clinical and experimental pharmacology · 2022
    Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

Ameya U AmritwarMood and Anxiety Program, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Christopher A LowryDepartment of Integrative Physiology and Center for Neuroscience, University of Colorado Boulder, Boulder, CO, USA.
Lisa A BrennerMilitary and Veteran Microbiome Consortium for Research and Education (MVM-CoRE).
Andrew J HoisingtonMilitary and Veteran Microbiome Consortium for Research and Education (MVM-CoRE).
Robert HamiltonDepartment of Medicine, Division of Allergy and Clinical Immunology, Johns Hopkins Asthma and Allergy Center, Baltimore, Maryland.
John W StillerMood and Anxiety Program, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Teodor T PostolacheMood and Anxiety Program, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
University of Maryland, Baltimore · USAllergy, Asthma and Clinical Research Center · USMental Illness Research, Education and Clinical Centers · USSt. Elizabeths Hospital · USUnited States Air Force Academy · USUniversity of Colorado Boulder · US

Funding

SEASONALITY OF SUICIDE AND AIRBORNE ALLERGENSR01MH074891 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI POSTOLACHE, TEODOR T · 2007 to 2009
$1.0M
Mood Worsening in Spring in Women with Depression and Tree-Pollen AllergyR21MH075891 · NIMH · UNIVERSITY OF MARYLAND BALTIMORE · PI POSTOLACHE, TEODOR T · 2006 to 2007
$363k
NIMH NIH HHS R01 MH074891NIMH NIH HHS R21 MH075891
6 · The paper itself

Abstract

A high proportion of suicides visit their medical provider in the month prior to death, but depression, suicidal thoughts, and substance use are seldom addressed. For the clinicians routinely treating a substantial patient population with allergic diseases, there are additional concerns, as allergy has been linked with both depression and suicidal behavior. While psychotropic medications may affect diagnosis of allergies, medications used to treat allergies impact mood and behavior. Thus, we present an overview of the overlap of allergic rhinitis with depression and suicidal behavior in adults, based on clinical and epidemiological data, and our research and clinical experience. In summary, we suggest: 1) inquiring among patients with allergies about personal and family history of depression, substance use disorders, suicidal ideation and attempts 2) increased mindfulness regarding the potential effects of allergy medications on mood and behavior; and 3) for people identified with certain types of depression or increased suicide risk, a systematic multilevel collaborative approach. While for practical reasons the majority of patients with depression will continue to be treated by general or family practitioners, the allergy-treating provider should always consider integrated care for bipolar, psychotic or suicidal depression and incomplete remission, or relapsing and highly recurrent course. While awaiting results of much needed basic and clinical research to guide clinical approach for patients with comorbid allergic rhinitis and depression, the simple steps recommended here are expected to improved clinical outcomes in depression, including, on a large scale, reduced premature deaths by suicide.

Indexed as

Allergic rhinitisDepressionInflammationSuicidal behaviorsuicidality

Identifiers

PMID28966902
PMCPMC5614510
OpenAlexW2604056665

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.