Trial reportTremor and other hyperkinetic movements (New York, N.Y.)2017
Digitizing Tablet and Fahn-Tolosa-Marín Ratings of Archimedes Spirals have Comparable Minimum Detectable Change in Essential Tremor.
Trial report in Tremor and other hyperkinetic movements (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 15 citations in OpenAlex.
- Longitudinal Changes in the Digitized Archimedes Spiral Drawing Test Following iTBS of the Left DLPFC in Parkinson's Disease: An Exploratory Feasibility Study.Journal of clinical medicine · 2026Article
- Essential Tremor and Digital Biomarkers: A Scoping Review Using the TRACE Framework to Map Readiness for Clinical Trials and Routine Practice.Tremor and other hyperkinetic movements (New York, N.Y.) · 2026Article
- Clinical Applications and Measurement Properties of the Digitized Archimedes Spiral Drawing Test: A Scoping Review.Movement disorders clinical practice · 2025Article
- Upper limb intention tremor assessment: opportunities and challenges in wearable technology.Journal of neuroengineering and rehabilitation · 2024Review
- Wearable Accelerometer and Gyroscope Sensors for Estimating the Severity of Essential Tremor.IEEE journal of translational engineering in health and medicine · 2024Article
- Video Motion Analysis as a Quantitative Evaluation Tool for Essential Tremor during Magnetic Resonance-Guided Focused Ultrasound Thalamotomy.Neurology international · 2023Article
- Non-invasive electrical stimulation of peripheral nerves for the management of tremor.Journal of the neurological sciences · 2022Review
- Article
- From null to midline: changes in head posture do not predictably change head tremor in cervical dystonia.Dystonia (Lausanne, Switzerland) · 2022Article
- Personalised profiling to identify clinically relevant changes in tremor due to multiple sclerosis.BMC medical informatics and decision making · 2019Article
- Automatic Analysis of Archimedes' Spiral for Characterization of Genetic Essential Tremor Based on Shannon's Entropy and Fractal Dimension.Entropy (Basel, Switzerland) · 2018Article
- A digital assessment system for evaluating kinetic tremor in essential tremor and Parkinson's disease.BMC neurology · 2018Article
- Estimating Change in Tremor Amplitude Using Clinical Ratings: Recommendations for Clinical Trials.Tremor and other hyperkinetic movements (New York, N.Y.) · 2018Article
- Using Portable Transducers to Measure Tremor Severity.Tremor and other hyperkinetic movements (New York, N.Y.) · 2016Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDrawing Archimedes spirals is a popular and valid method of assessing action tremor in the upper limbs. We performed the first blinded comparison of Fahn-Tolosa-Marín (FTM) ratings and tablet measures of essential tremor to determine if a digitizing tablet is better than 0-4 ratings in detecting changes in essential tremor that exceed random variability in tremor amplitude.
methodsThe large and small spirals of FTM were drawn with each hand on two consecutive days by 14 men and four women (age 60±8.7 years [mean±SD]) with mild to severe essential tremor. The drawings were simultaneously digitized with a digitizing tablet. Tremor in each digitized drawing was computed with spectral analysis in an independent laboratory, blinded to the clinical ratings. The mean peak-to-peak tremor displacement (cm) in the four spirals and mean FTM ratings were compared statistically.
resultsTest-retest intraclass correlations (ICCs) (two-way random single measures, absolute agreement) were excellent for the FTM ratings (ICC 0.90, 95% CI 0.76-0.96) and tablet (ICC 0.97, 95% CI 0.91-0.99). Log DISCUSSION: Digitizing tablets are much more precise than clinical ratings, but this advantage is mitigated by the natural variability in tremor. Nevertheless, the digitizing tablet is a robust method of quantifying tremor that can be used in lieu of or in combination with clinical ratings.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.