Evidence map›Paper›PMID 28966809›Full record

ReviewAging and disease2017

Ovarian Cancer Management in the Oldest Old: Improving Outcomes and Tailoring Treatments.

Lucia Tortorella, Giuseppe Vizzielli, Domenico Fusco, William C Cho, Roberto Bernabei, Giovanni Scambia, Giuseppe Colloca

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Aging and disease, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucia Tortorella1Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy.
Giuseppe Vizzielli1Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy.
Domenico Fusco2Geriartic Department, Fondazione Policlinico A.Gemelli, Rome, Italy.
William C Cho3Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong.
Roberto Bernabei2Geriartic Department, Fondazione Policlinico A.Gemelli, Rome, Italy.
Giovanni Scambia1Division of Gynecologic Oncology, Catholic University of the Sacred Heart, Rome, Italy.
Giuseppe Colloca2Geriartic Department, Fondazione Policlinico A.Gemelli, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ovarian cancer is the most common cause of death from gynecological cancers in developed countries. It is a common disease of older women at or above 63 years upon diagnosis. Thanks to advance in new treatments, mortality from ovarian cancer has declined in developed countries in the last decade. This decline in mortality rate is unevenly distributed across the age-spectrum. While mortality in younger women has decreased 21.7%, for elderly women it has declined only 2.2%. Even if ovarian cancer is clearly a disease of the elderly, older women are underrepresented in clinical trials, and scant evidence exists for the treatment of women older than 80 years. Moreover, older women are frequently undertreated, receive less chemotherapy and less combination of surgery and chemotherapy, despite the fact that this is considered the optimal treatment modality. This may be mainly due to the lack of evidence and physician's confidence in the management of elderly women with ovarian cancer. In this review, we focus on the management of older women with ovarian cancer, considering geriatric features tied to this population.

Indexed as

elderlyfrailtyovarian cancer

Identifiers

PMID28966809
PMCPMC5614329

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.