Evidence map›Paper›PMID 28966792›Full record

ArticleJournal of materials chemistry. B2017

Cationic Acrylate Oligomers Comprising Amino Acid Mimic Moieties Demonstrate Improved Antibacterial Killing Efficiency.

James L Grace, Alysha G Elliott, Johnny X Huang, Elena K Schneider, Nghia P Truong, Matthew A Cooper, Jian Li, Thomas P Davis, John F Quinn, Tony Velkov and 1 more

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 42 citations in OpenAlex.

  1. Ring-opening metathesis polymerization ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  2. Article
  3. Green Silver Nanoparticles Formed byNanomaterials (Basel, Switzerland) · 2020
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 4 countries.

James L GraceARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Alysha G ElliottInstitute of Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia, 4072.
Johnny X HuangInstitute of Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia, 4072.
Elena K SchneiderDrug Delivery, Disposition and Dynamics Theme, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Nghia P TruongARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Matthew A CooperInstitute of Molecular Biosciences, The University of Queensland, Brisbane, QLD, Australia, 4072.
Jian LiDrug Delivery, Disposition and Dynamics Theme, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Thomas P DavisARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
John F QuinnARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Tony VelkovDrug Delivery, Disposition and Dynamics Theme, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Michael R WhittakerARC Centre of Excellence in Convergent Bio-Nano Science and Technology, Monash University, 381 Royal Pde, Parkville, VIC, Australia, 3052.
Australian Regenerative Medicine Institute · AUThe University of Queensland · AUDiscovery Institute · US

Funding

New Tricks for 'Old' Drugs: PK/PD of Polymyxin Nonantibiotic CombinationsR01AI111965 · NIAID · MONASH UNIVERSITY · PI LI, JIAN · 2014 to 2018
$4.3M
NIAID NIH HHS R01 AI111965
6 · The paper itself

Abstract

Cu(0)-mediated polymerization was employed to synthesize a library of structurally varied cationic polymers and their application as antibacterial peptide mimics was assessed. Eight platform polymers were first synthesized with low degrees of polymerization (DP) using (2-Boc-amino)ethyl acrylate as the monomer and either ethyl α-bromoisobutyrate or dodecyl 2-bromoisobutyrate as the initiator (thus providing hydrocarbon chain termini of C

Identifiers

PMID28966792
PMCPMC5615857
OpenAlexW2565224595

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.