Evidence map›Paper›PMID 28966790›Full record

ArticleJournal of materials chemistry. B2017

A biomaterial approach to cell reprogramming and differentiation.

Joseph Long, Hyejin Kim, Dajeong Kim, Jong Bum Lee, Deok-Ho Kim

Abstract read
In one paragraph

Article in Journal of materials chemistry. B, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Review
  3. Engineering Three-Dimensional Vascularized Cardiac Tissues.Tissue engineering. Part B, Reviews · 2022
    Review
  4. Article
  5. Article
  6. Progress of Nanotechnology in Diabetic Retinopathy Treatment.International journal of nanomedicine · 2021
    Review
  7. Article
  8. Nanotechnology in regenerative ophthalmology.Advanced drug delivery reviews · 2019
    Review
  9. Review
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joseph LongDepartment of Bioengineering, University of Washington, Seattle WA, 98195, USA.
Hyejin KimDepartment of Chemical Engineering, University of Seoul, Seoul, 02504, South Korea.
Dajeong KimDepartment of Chemical Engineering, University of Seoul, Seoul, 02504, South Korea.
Jong Bum LeeDepartment of Chemical Engineering, University of Seoul, Seoul, 02504, South Korea.
Deok-Ho KimDepartment of Bioengineering, University of Washington, Seattle WA, 98195, USA.

Funding

UW Post-Baccalaureate Research Education Program (PREP)R25GM086304 · NIGMS · UNIVERSITY OF WASHINGTON · PI Gabriele Varani · 2011 to 2026
$5.7M
A NANOPATTERNED MEA-BASED FUNCTIONAL PHENOTYPING ASSAY FOR DRUG-INDUCED CARDIOTOXICITY SCREENINGR01HL135143 · NHLBI · UNIVERSITY OF WASHINGTON · PI KIM, DEOK-HO · 2017 to 2021
$1.9M
TISSUE ENGINEERED HUMAN NEUROMUSCULAR JUNCTIONS FOR MODELING AXONAL NEUROPATHYR01NS094388 · NINDS · UNIVERSITY OF WASHINGTON · PI KIM, DEOK-HO · 2017 to 2021
$1.7M
Injectable myocardial matrix-grapheme composite hydrogels for functional cardiac tissue engineeringR21EB020132 · NIBIB · UNIVERSITY OF WASHINGTON · PI KIM, DEOK-HO · 2016 to 2017
$435k
NHLBI NIH HHS R01 HL135143NIBIB NIH HHS R21 EB020132NIGMS NIH HHS R25 GM086304NINDS NIH HHS R01 NS094388
6 · The paper itself

Abstract

Cell reprogramming of somatic cells into pluripotent states and subsequent differentiation into certain phenotypes has helped progress regenerative medicine research and other medical applications. Recent research has used viral vectors to induce this reprogramming; however, limitations include low efficiency and safety concerns. In this review, we discuss how biomaterial methods offer potential avenues for either increasing viability and downstream applicability of viral methods, or providing a safer alternative. The use of non-viral delivery systems, such as electroporation, micro/nanoparticles, nucleic acids and the modulation of culture substrate topography and stiffness have generated valuable insights regarding cell reprogramming.

Indexed as

biomaterialsbiophysical cuescell reprogrammingnon-viral delivery

Identifiers

PMID28966790
PMCPMC5616208

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.