Evidence map›Paper›PMID 28966642›Full record

ArticleNeural regeneration research2017

Spreading depression and focal venous cerebral ischemia enhance cortical neurogenesis.

Ryo Tamaki, Samuel Ige Orie, Beat Alessandri, Oliver Kempski, Axel Heimann

Open access · goldAbstract read
In one paragraph

Article in Neural regeneration research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ryo TamakiDepartment of Neurosurgery, Nara Medical University, Nara, Japan.
Samuel Ige OrieUniversity Medical Center of the Johannes Gutenberg-University of Mainz, Institute for Neurosurgical Pathophysiology, Mainz, Germany.
Beat AlessandriUniversity Medical Center of the Johannes Gutenberg-University of Mainz, Institute for Neurosurgical Pathophysiology, Mainz, Germany.
Oliver KempskiUniversity Medical Center of the Johannes Gutenberg-University of Mainz, Institute for Neurosurgical Pathophysiology, Mainz, Germany.
Axel HeimannUniversity Medical Center of the Johannes Gutenberg-University of Mainz, Institute for Neurosurgical Pathophysiology, Mainz, Germany.ORCID 0000-0003-2510-3228
University Medical Center of the Johannes Gutenberg University Mainz · DEJohannes Gutenberg University Mainz · DENara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endogenous neurogenesis can arise from a variety of physiological stimuli including exercise, learning, or "enriched environment" as well as pathological conditions such as ischemia, epilepsy or cortical spreading depression. Whether all these conditions use a common trigger to set off endogenous neurogenesis is yet unclear. We hypothesized that cortical spreading depression (CSD) induces neurogenesis in the cerebral cortex and dentate gyrus after cerebral venous ischemia. Forty-two Wistar rats alternatively underwent sham operation (Sham), induction of ten CSDs or venous ischemia provoked

Indexed as

adult neurogenesiscerebral cortexcortical spreading depressionnerve regenerationneural precursor cellsneural regenerationneuronpenumbrastem cellstwo-vein occlusion

Identifiers

PMID28966642
PMCPMC5607822
OpenAlexW2747861125

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.