Evidence map›Paper›PMID 28966560›Full record

ArticleCrystal growth & design2017

Crystal Nucleation Using Surface-Energy-Modified Glass Substrates.

Kyle A Nordquist, Kevin M Schaab, Jierui Sha, Andrew H Bond

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Crystal growth & design, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 8 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kyle A NordquistDeNovX, 3440 South Dearborn Street, Lab 204 S, Chicago, Illinois 60616, United States.
Kevin M SchaabDeNovX, 3440 South Dearborn Street, Lab 204 S, Chicago, Illinois 60616, United States.
Jierui ShaDeNovX, 3440 South Dearborn Street, Lab 204 S, Chicago, Illinois 60616, United States.
Andrew H BondDeNovX, 3440 South Dearborn Street, Lab 204 S, Chicago, Illinois 60616, United States.
Denovx (United States) · US

Funding

Microdomain Thermal Perturbations for Enhanced Nucleation of Proteins-Administrative Supplement-Instrumentation-Dynamic Light Scattering of Protein AggregatesR44GM108158 · NIGMS · DENOVX, LLC · PI BOND, ANDREW H. · 2017 to 2018
$1.9M
Microdomain Thermal Perturbations for Enhanced Nucleation of ProteinsR43GM108158 · NIGMS · DENOVX, LLC · PI BOND, ANDREW H. · 2015 to 2015
$224k
6 · The paper itself

Abstract

Systematic surface energy modifications to glass substrates can induce nucleation and improve crystallization outcomes for small molecule active pharmaceutical ingredients (APIs) and proteins. A comparatively broad probe for function is presented in which various APIs, proteins, organic solvents, aqueous media, surface energy motifs, crystallization methods, form factors, and flat and convex surface energy modifications were examined. Replicate studies (

Identifiers

PMID28966560
PMCPMC5613273
OpenAlexW2738941538

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.