Evidence map›Paper›PMID 28966514›Full record

ArticleAnnals of dermatology2017

A Study of the Changes of T Helper 17 Cells and Regulatory T Cells in Herpes Zoster.

Min Sung Kim, Dong Jin Kim, Chan Ho Na, Bong Seok Shin

Abstract read
In one paragraph

Article in Annals of dermatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Serum Inflammatory Cytokine Levels in Herpes Zoster Patients and Their Association with Postherpetic Neuralgia: A Prospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  3. Article
  4. The Binary Classification of Protein Kinases.Journal of inflammation research · 2021
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Min Sung KimDepartment of Dermatology, Chosun University School of Medicine, Gwangju, Korea.
Dong Jin KimDepartment of Dermatology, Chosun University School of Medicine, Gwangju, Korea.
Chan Ho NaDepartment of Dermatology, Chosun University School of Medicine, Gwangju, Korea.
Bong Seok ShinDepartment of Dermatology, Chosun University School of Medicine, Gwangju, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImmunosuppression and age-related deficiencies in cell-mediated immunity are important factors for the reactivation of latent varicella-zoster virus (VZV). CD4

objectiveWe analyzed Treg cells and Th17 cells in patients with herpes zoster and investigated their relationship with the reactivation of latent VZV.

methodsTreg and Th17 cells in peripheral blood and the ratio of Th17 to Treg cells were examined in patients with herpes zoster and healthy controls. Changes between pre-treatment and post-treatment estimates of Treg and Th17 cells and clinical parameters in patients with herpes zoster were also analyzed.

resultsThe proportion of circulating Th17 cells and the Th17/Treg cell ratio were significantly higher in patients with herpes zoster than controls (

conclusionAn imbalance between Th17 and Treg cells is associated with the reactivation of VZV, which may contribute to pathogenesis of herpes zoster.

Indexed as

Herpes zosterRegulatory T cellsTh17 cellsVaricella-zoster virus

Identifiers

PMID28966514
PMCPMC5597651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.