Evidence map›Paper›PMID 28966451›Full record

ReviewProceedings (Baylor University. Medical Center)2017

Usefulness of radium-223 in patients with bone metastases.

Nishant Gupta, Arushi Devgan, Itisha Bansal, Thomas D Olsavsky, Shuo Li, Ahmed Abdelbaki, Yogesh Kumar

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Proceedings (Baylor University. Medical Center), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Evaluation ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2025
    Article
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nishant GuptaDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Arushi DevganDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Itisha BansalDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Thomas D OlsavskyDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Shuo LiDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Ahmed AbdelbakiDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).
Yogesh KumarDepartment of Radiology, Columbia University Medical Center, New York, New York (Gupta); Department of Radiology, University of Arkansas, Little Rock, Arkansas (Devgan); Department of Anesthesiology, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, New York (Bansal); Department of Nuclear Medicine, St. Vincent's Medical Center, Bridgeport, Connecticut (Olsavsky); Department of Radiology, Yale New Haven Health at Bridgeport Hospital, Bridgeport, Connecticut (Li, Abdelbaki); and Columbia University at Bassett Healthcare, Cooperstown, New York (Kumar).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Castration-resistant prostate osseous metastases can be challenging to treat. There is a new era of clinical advancement with the Food and Drug Administration approval of radium-223 for use in these patients. Radium-223 is the only clinically used therapeutic radiopharmaceutical that emits alpha particles, making it extremely safe for therapeutic purposes for the patient as well as close contacts. This review discusses radium-223's mechanism of action, pharmacokinetics, indications, and safety profile, as well as findings of concluded clinical trials.

Identifiers

PMID28966451
PMCPMC5595381

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.