ArticleThe Canadian veterinary journal = La revue veterinaire canadienne2017
Feline meningoencephalomyelitis of unknown origin: A retrospective analysis of 16 cases.
Article in The Canadian veterinary journal = La revue veterinaire canadienne, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Feline neurological disease in a veterinary referral hospital in the UK: clinical diagnosis, neuroanatomical localisation and VITAMIN D-based aetiological distribution.Journal of feline medicine and surgery · 2026Article
- Usefulness of cerebrospinal fluid analysis in dogs and cats with suspected intracranial disease and normal magnetic resonance imaging.Frontiers in veterinary science · 2025Article
- Of potential new treatment targets and polythetic approach in meningoencephalitis of unknown origin: a review.Frontiers in veterinary science · 2024Review
- Demographics, clinical findings and diagnoses of cranial thoracic myelopathies (T1-T6 vertebrae) in cats.Journal of feline medicine and surgery · 2023Article
- Meningoencephalomyelitis of Unknown Origin in Cats: A Case Series Describing Clinical and Pathological Findings.Frontiers in veterinary science · 2020Article
- Meningoencephalitis of unknown origin with predominant cerebellar involvement in a cat: clinical, MRI and pathological findings.JFMS open reportsArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to describe the signalment, clinical signs, magnetic resonance imaging (MRI) findings, cerebrospinal fluid (CSF) analysis, treatment, and outcome of feline meningoencephalomyelitis of unknown origin (FMUO). Medical records from 16 cats meeting the inclusion criteria of CSF pleocytosis, negative CSF polymerase chain reaction (PCR)-infectious disease results, and characteristic MRI findings were retrospectively reviewed. Median age was 9.4 years. Clinical signs included ataxia, proprioceptive deficits, seizures, and spinal hyperesthesia. The CSF nucleated cell count was increased (median 70.7 cells/μL), with predominantly mixed pleocytosis and CSF protein concentration was increased in 15/16 cats. Magnetic resonance imaging showed intraparenchymal infiltrative ill-defined lesions in 13 cases. All cats received a corticosteroid-based treatment protocol; additional therapies included lomustine, cytarabine, and anticonvulsant medications. Mild neurological signs were recorded in 5/12 cats but 7/12 cats were neurologically normal at re-examination. This represents the first study of feline MUO, highlighting FMUO as an important differential diagnosis in cats with variable neurological presentation. Prognosis appears to be good with immunomodulatory therapy.
Indexed as
Identifiers
28966357PMC5603942W3025116154What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.