SynthesisEBioMedicine2017
How Long can we Store Blood Samples: A Systematic Review and Meta-Analysis.
Synthesis in EBioMedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 77 citations in OpenAlex.
- The impact of different preanalytical methods related to CA 15-3 determination in frozen human blood samples: a systematic review.Systematic reviews · 2021Pooled it
- The impact of pre-analytical variations on biochemical analytes stability: A systematic review.Journal of clinical laboratory analysis · 2020Pooled it
- FlowSpot Enables Decentralized Phenotypic and Functional Cellular Immune Profiling from Dried Blood Spots.bioRxiv : the preprint server for biology · 2026Article
- Hematological Parameters in Sheep: Variability, Determinants, and Applications in Flock Health Management.Animals : an open access journal from MDPI · 2026Review
- Article
- Effects of sample storage time and temperature on equine complete blood counts.Journal of equine veterinary science · 2026Article
- Time stability of Intensive Care Infection Score (ICIS) as a cellular hematology biomarker for infection in critically ill patients.Scientific reports · 2026Article
- First hematological and biochemical findings in a rehabilitated giant pangolin (Frontiers in veterinary science · 2026Article
- Assessment of the stability of 20 biochemical analytes in serum and whole blood samples after storage at nonstandard temperatures.Practical laboratory medicine · 2026Article
- Advancing Intervertebral Disc Biology via Omics: Implications for Nucleus Pulposus Progenitor Cell-Based Regeneration.JOR spine · 2025Review
- Distribution of Hematologic Parameters of Complete Blood Count in Anemic and Nonanemic Children in a Mining-Exposed Highland Peruvian Community.International journal of environmental research and public health · 2025Article
- Advances toward At-Home Measurements of Complete Blood Cell Counts and Other Hematological Parameters.Analytical chemistry · 2025Review
- The impact of pre-analytical factors on plasma biomarkers for Alzheimer's disease: The ASPREE Healthy Ageing Biobank.The journal of prevention of Alzheimer's disease · 2025Article
- Dissecting immunophenotypic diversity in multiple myeloma via mass cytometry: a call for harmonized gating strategies.Frontiers in immunology · 2025Review
- Analysis of plasma metabolomes from 11 309 subjects in five population-based cohorts.Scientific reports · 2024Article
- miRNA Studies in Glaucoma: A Comprehensive Review of Current Knowledge and Future Perspectives.International journal of molecular sciences · 2023Review
- IMPACT OF AIR TRANSPORT ON BLOOD SAMPLE QUALITY.Acta clinica Croatica · 2023Article
- Causes of Moderate and Severe Anaemia in a High-HIV and TB-Prevalent Adult Population in the Eastern Cape Province, South Africa.International journal of environmental research and public health · 2023Article
- Impact of potassium test sample rejections on routine laboratory service, South Africa.African journal of laboratory medicine · 2023Article
- Circular RNAs in peripheral blood mononuclear cells are more stable than linear RNAs upon sample processing delay.Journal of cellular and molecular medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the effect of storage time and temperature on complete blood count (CBC) and comprehensive metabolic panel (CMP) testing.
methodsPubMed, EMBASE, the Cochrane Library of Systematic Reviews, Web of Science (WOS), China National Knowledge Infrastructure (CNKI), WanFang databases and SinoMed databases were searched up to May 2017. Clinical trials with adult whole blood samples were identified. Paired reviewers independently screened, extracted data and evaluated the quality of evidence (MINORS tool). Analyses were conducted using Revman 5.3 and Stata 14.0.
resultsA total of 89 studies were confirmed. For CBC, except MPV, most parameters were stable at least for 24h. Some indices, such as WBC, PLt, HCT, HGB and MCH were stable up to 3 d. However, stable CMP test results could only be acquired within 12h. at 4°C, including GLU, AST, ALT, Na, ALB, Cl, DBIL, TC, TG and ALP. Values were less stable when stored at RT.
conclusionsSpecimens stored >12h. for CMP may generate unreliable results. For CBC, samples could reliably be stored for 24h. For longer storage, refrigeration (at 4°C) would be a better choice.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.