Evidence map›Paper›PMID 28965517›Full record

ReviewVisual neuroscience2017

Not a one-trick pony: Diverse connectivity and functions of the rodent lateral geniculate complex.

Aboozar Monavarfeshani, Ubadah Sabbagh, Michael A Fox

Open access · bronzeAbstract readReview
In one paragraph

Review in Visual neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 89 citations in OpenAlex.

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  12. Mapping the Retina onto the Brain.Cold Spring Harbor perspectives in biology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Aboozar MonavarfeshaniDevelopmental and Translational Neurobiology Center,Virginia Tech Carilion Research Institute,Roanoke,Virginia.
Ubadah SabbaghDevelopmental and Translational Neurobiology Center,Virginia Tech Carilion Research Institute,Roanoke,Virginia.
Michael A FoxDevelopmental and Translational Neurobiology Center,Virginia Tech Carilion Research Institute,Roanoke,Virginia.
Carilion Clinic · USVirginia Tech · US

Funding

Regulation of nuclei-specific retinogeniculate targetingR01EY021222 · NEI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI FOX, MICHAEL A · 2011 to 2021
$3.8M
Toxoplasma gondii Regulation of Host GABAergic SignalingR01AI124677 · NIAID · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI BLADER, IRA J, FOX, MICHAEL A · 2016 to 2020
$2.7M
Investigating the Mechanism of Optic Nerve Hypoplasia Associated with CASK MutationR01EY024712 · NEI · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI MUKHERJEE, KONARK · 2015 to 2019
$2.0M
NEI NIH HHS R01 EY021222NEI NIH HHS R01 EY024712NIAID NIH HHS R01 AI124677
6 · The paper itself

Abstract

Often mislabeled as a simple relay of sensory information, the thalamus is a complicated structure with diverse functions. This diversity is exemplified by roles visual thalamus plays in processing and transmitting light-derived stimuli. Such light-derived signals are transmitted to the thalamus by retinal ganglion cells (RGCs), the sole projection neurons of the retina. Axons from RGCs innervate more than ten distinct nuclei within thalamus, including those of the lateral geniculate complex. Nuclei within the lateral geniculate complex of nocturnal rodents, which include the dorsal lateral geniculate nucleus (dLGN), ventral lateral geniculate nucleus (vLGN), and intergeniculate leaflet (IGL), are each densely innervated by retinal projections, yet, exhibit distinct cytoarchitecture and connectivity. These features suggest that each nucleus within this complex plays a unique role in processing and transmitting light-derived signals. Here, we review the diverse cytoarchitecture and connectivity of these nuclei in nocturnal rodents, in an effort to highlight roles for dLGN in vision and for vLGN and IGL in visuomotor, vestibular, ocular, and circadian function.

Indexed as

AnimalsAxonsGeniculate BodiesRetinal Ganglion CellsRodentiaVisual PathwaysIntergeniculate leafletLateral geniculate nucleusRetinal ganglion cellsRetinogeniculateThalamus

Identifiers

PMID28965517
PMCPMC5755970
OpenAlexW2724288537

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.