Evidence map›Paper›PMID 28965492›Full record

ArticleBMC medicine2017

Can learning health systems help organisations deliver personalised care?

Bright I Nwaru, Charles Friedman, John Halamka, Aziz Sheikh

Abstract read
In one paragraph

Article in BMC medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
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  5. Learning health system linchpins: information exchange and a common data model.Journal of the American Medical Informatics Association : JAMIA · 2025
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  11. Review
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  16. From LearningLearning health systems · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Bright I NwaruKrefting Research Centre, Department of Internal Medicine, University of Gothenburg, Gothenburg, Sweden.
Charles FriedmanDepartment of Learning Health Sciences, University of Michigan, Ann Arbor, MI, USA.
John HalamkaBeth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA.
Aziz SheikhKrefting Research Centre, Department of Internal Medicine, University of Gothenburg, Gothenburg, Sweden. aziz.sheikh@ed.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is increasing international policy and clinical interest in developing learning health systems and delivering precision medicine, which it is hoped will help reduce variation in the quality and safety of care, improve efficiency, and lead to increasing the personalisation of healthcare. Although reliant on similar policies, informatics tools, and data science and implementation research capabilities, these two major initiatives have thus far largely progressed in parallel. In this opinion piece, we argue that they should be considered as complementary, synergistic initiatives whereby the creation of learning health systems infrastructure can support and catalyse the delivery of precision medicine that maximises the benefits and minimises the risks associated with treatments for individual patients. We illustrate this synergy by considering the example of treatments for asthma, which is now recognised as an umbrella term for a heterogeneous group of related conditions.

Indexed as

Delivery of Health CareHumansLearningPrecision MedicineAsthmaLearning health systemP4 medicinePersonalised medicinePrecision medicineStratified medicine

Identifiers

PMID28965492
PMCPMC5623976

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.