Evidence map›Paper›PMID 28965267›Full record

ArticleEuropean journal of pediatrics2017

Exercise performance and quality of life in children with cystic fibrosis and mildly impaired lung function: relation with antibiotic treatments and hospitalization.

Kristof Vandekerckhove, Michiel Keyzer, Jasper Cornette, Ilse Coomans, Filip Pyl, Frans De Baets, Petra Schelstraete, Filomeen Haerynck, Daniel De Wolf, Sabine Van Daele and 1 more

Registry-linked trialAbstract read
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In one paragraph

Article in European journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05173194 (Effects of a Remotely Supervised Exercise Program on Inflammatory Markers, Muscle Strength and Lung Function in Adult Patients With Cystic Fibrosis), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05173194 nacompletednot on this mapstarted 2021, after this paper: background citation

Effects of a Remotely Supervised Exercise Program on Inflammatory Markers, Muscle Strength and Lung Function in Adult Patients With Cystic Fibrosis

TypeinterventionalSponsorUniversidad Europea de MadridRan2021 to 2021Enrolled32ConditionsCystic FibrosisArmsExercise
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Kristof VandekerckhoveDepartment of Pediatric Cardiology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium. Kristof.vandekerckhove@uzgent.be.ORCID http://orcid.org/0000-0002-1481-0878
Michiel KeyzerDepartment of Pediatric Cardiology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Jasper CornetteDepartment of Pediatric Cardiology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Ilse CoomansDepartment of Pediatric Cardiology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Filip PylDepartment of Paediatric Pulmonology, Ghent University Belgium, Ghent, Belgium.
Frans De BaetsDepartment of Paediatric Pulmonology, Ghent University Belgium, Ghent, Belgium.
Petra SchelstraeteDepartment of Paediatric Pulmonology, Ghent University Belgium, Ghent, Belgium.
Filomeen HaerynckDepartment of Paediatric Pulmonology, Ghent University Belgium, Ghent, Belgium.
Daniel De WolfDepartment of Pediatric Cardiology, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
Sabine Van DaeleDepartment of Paediatric Pulmonology, Ghent University Belgium, Ghent, Belgium.
Jan BooneDepartment of Movement and Sport Sciences, Ghent University, Ghent, Belgium.
Ghent University Hospital · BEGhent University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluates the impact of antibiotic treatments and hospitalization on exercise performance and health-related quality of life (QOL) in children with mild cystic fibrosis (CF) lung disease. Forty-seven children between 7 and 17 years with mild CF underwent a maximal exercise test including spiro-ergometry and filled out a QOL-questionnaire (PedsQL™). Amount of antibiotic treatments (AB) and hospitalization days in the last 3 years were reviewed. FEV1% was mildly decreased (91.7 ± 17.9 L/min, p = 0.02). Maximal oxygen consumption (VO

conclusionPatients with mild CF lung disease have good exercise performance although still lower than the normal population. VO2max% is affected by number of antibiotic treatments over a longer period. There is an impact of hospitalization days on quality of life. What is Known: • Children with CF have lower exercise performance; there is an association between hospitalization frequency and exercise performance • Quality of life is diminished in children with CF and influenced by respiratory infections What is New: • Even patients with mild CF lung disease have lower maximal exercise performance (VO

Indexed as

Exercise ToleranceQuality of LifeAdolescentAnti-Bacterial AgentsChildCystic FibrosisExercise TestFemaleHospitalizationHumansMaleOxygen ConsumptionRetrospective StudiesSeverity of Illness IndexAnti-Bacterial AgentsChildrenCystic fibrosisExercise performanceExercise testingRespiratory exacerbations

Identifiers

PMID28965267
OpenAlexW2759568684

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.