Evidence map›Paper›PMID 28965228›Full record

SynthesisDigestive diseases and sciences2017

Chromoendoscopy, Narrow-Band Imaging or White Light Endoscopy for Neoplasia Detection in Inflammatory Bowel Diseases.

Ofir Har-Noy, Lior Katz, Tomer Avni, Robert Battat, Talat Bessissow, Diana E Yung, Tal Engel, Anastasios Koulaouzidis, Rami Eliakim, Shomron Ben-Horin and 1 more

Abstract readMeta-AnalysisReview
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 45 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Capsule Endoscopy: Pitfalls and Approaches to Overcome.Diagnostics (Basel, Switzerland) · 2021
    Review
  7. Review
  8. Article
  9. Article
  10. Imaging Inflammation and Infection in the Gastrointestinal Tract.International journal of molecular sciences · 2019
    Review
  11. Gastrointestinal diagnosis using non-white light imaging capsule endoscopy.Nature reviews. Gastroenterology & hepatology · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Ofir Har-NoyGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel. ofirharnoy@gmail.com.ORCID 0000-0002-4099-1342
Lior KatzGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel.
Tomer AvniSackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
Robert BattatDivision of Gastroenterology, McGill University Health Center, Montréal, QC, Canada.
Talat BessissowDivision of Gastroenterology, McGill University Health Center, Montréal, QC, Canada.
Diana E YungCentre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, UK.
Tal EngelGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel.
Anastasios KoulaouzidisCentre for Liver and Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, UK.
Rami EliakimGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel.
Shomron Ben-HorinGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel.
Uri KopylovGastroenterology Department, Sheba Medical Center, Ramat Gan, Israel.
Tel Aviv University · ILEdinburgh Royal Infirmary · GBMcGill University Health Centre · CASheba Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies have confirmed an increased risk of colorectal cancer in patients with ulcerative colitis; hence, surveillance is recommended. Optional modalities include white light endoscopy (WLE) or dye-spray chromoendoscopy. However, narrow-band imaging (NBI) is still not considered comparable to chromoendoscopy.

aimThe aim of this study was to compare the diagnostic yield (DY) of WLE, chromoendoscopy, NBI for detection of neoplasia in patients with inflammatory bowel disease (IBD) by performing a meta-analysis of the existing literature.

methodsWe searched databases for prospective studies. For each modality, we performed comparative per-lesion analysis (any neoplasia detection) and per-patient analysis (patient with neoplastic lesions). Meta-analysis was performed using fixed-effect model unless heterogeneity was high. Odds ratios (ORs) with 95% CIs were calculated and pooled.

resultsFive studies compared chromoendoscopy to WLE. Chromoendoscopy (n = 361) was superior to WLE (n = 358) with per-patient analysis OR 2.05 (95% CI 1.26, 3.35) and per-lesion analysis OR 2.79 (95% CI 2.08, 3.73). High-definition (HD) chromoendoscopy was superior to HD-WLE with per-lesion analysis OR 2.48 (95% CI 1.55, 3.97). In four studies comparing NBI to WLE (n = 305), no difference was found in per-patient analysis OR 0.97 (95% CI 0.62, 1.53) and per-lesion analysis OR 0.94 (95% CI 0.63, 1.4). In two studies comparing CE to NBI (n = 104), no difference was found in per-patient analysis OR 1.0 (95% CI 0.51, 1.95) and per-lesion analysis OR 1.29 (95% CI 0.69, 2.41).

conclusionChromoendoscopy is superior to WLE for detection of dysplasia in IBD, even with HD endoscopy. No difference in DY could be demonstrated for NBI in comparison with other modalities.

Indexed as

Narrow Band ImagingColitis, UlcerativeColonColonoscopyColorectal NeoplasmsHumansOdds RatioPredictive Value of TestsReproducibility of ResultsRisk FactorsChromoendoscopyDiagnostic testsInflammatory bowel diseaseMeta-analysesUlcerative colitis

Identifiers

PMID28965228
OpenAlexW2759377679

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.