Evidence map›Paper›PMID 28965192›Full record

ArticleDigestive diseases and sciences2017

Repeated Oral Exposure to N

Nesreen ALJahdali, Pascale Gadonna-Widehem, Carine Delayre-Orthez, David Marier, Benjamin Garnier, Franck Carbonero, Pauline M Anton

Abstract read
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In one paragraph

Article in Digestive diseases and sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
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  8. The role of chronic kidney disease-associated dysbiosis in cardiovascular disease.Experimental biology and medicine (Maywood, N.J.) · 2019
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nesreen ALJahdaliCell and Molecular Biology Program, University of Arkansas, 2650 Young Avenue, Fayetteville, AR, 72704, USA.
Pascale Gadonna-WidehemExpression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France.
Carine Delayre-OrthezExpression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France.
David MarierExpression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France.
Benjamin GarnierExpression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France.
Franck CarboneroCell and Molecular Biology Program, University of Arkansas, 2650 Young Avenue, Fayetteville, AR, 72704, USA. fgcarbon@uark.edu.ORCID 0000-0003-3389-3725
Pauline M AntonExpression des Gènes et Régulation Epigénétique par l'Aliment UP 2012.10.101., Institut Polytechnique UniLaSalle, 19 rue Pierre Waguet, 60000, Beauvais, France.
University of Arkansas at Fayetteville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDiet is suggested to participate in the etiology of inflammatory bowel diseases (IBD). Repeated exposure to Maillard reaction products (MRPs), molecules resulting from reduction reactions between amino acids and sugars during food heating, has been reported to be either potentially detrimental or beneficial to health.

aimsThe aim of this study is to determine the effect of repeated oral ingestion of N

methodsMice received either saline (control) or N

resultsDaily oral administration of N

conclusionsRepeated oral exposure to CML limits dysbiosis in experimental colitis. IBD patients may modulate their microbiota profile by regulating the level and type of dietary MRP consumption.

Indexed as

Administration, OralAnimalsColitisDisease Models, AnimalDrug Evaluation, PreclinicalDysbiosisEatingGastrointestinal MicrobiomeGlycation End Products, AdvancedLysineMaleMice, Inbred BALB CNeutrophil InfiltrationGlycation End Products, AdvancedLysineN(6)-carboxymethyllysineDextran sulfate sodium salt colitisInflammationIntestinal microbiomeMaillard reaction productsN ε-CarboxymethyllysineTrinitrobenzenesulfonic acid colitis

Identifiers

PMID28965192
OpenAlexW2758310474

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.