Evidence map›Paper›PMID 28965093›Full record

ArticleBMJ open2017

Quantifying sociodemographic and income disparities in medical therapy and lifestyle among symptomatic patients with suspected coronary artery disease: a cross-sectional study in North America.

Joseph A Ladapo, Adrian Coles, Rowena J Dolor, Daniel B Mark, Lawton Cooper, Kerry L Lee, Jonathan Goldberg, Michael D Shapiro, Udo Hoffmann, Pamela S Douglas

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01174550 (PROspective Multicenter Imaging Study for Evaluation of Chest Pain - The PROMISE Trial), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01174550 nacompletednot on this map

PROspective Multicenter Imaging Study for Evaluation of Chest Pain - The PROMISE Trial

TypeinterventionalSponsorDuke UniversityRan2010 to 2014Enrolled10,003ConditionsChest PainArmsCoronary Angiography, Stress Echocardiogram, Nuclear Stress Test, Exercise Electrocardiogram
3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Joseph A LadapoDivision of General Internal Medicine and Health Services Research, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
Adrian ColesDepartment of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Rowena J DolorDepartment of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Daniel B MarkDepartment of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Lawton CooperNational Heart, Lung, and Blood Institute, Bethesda, Maryland, USA.
Kerry L LeeDepartment of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.
Jonathan GoldbergLouis Stokes Cleveland VA Medical Center, Cleveland, Ohio, USA.
Michael D ShapiroOregon Health and Science University, Portland, Oregon, USA.
Udo HoffmannDepartment of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Pamela S DouglasDepartment of Medicine, Duke Clinical Research Institute, Duke University School of Medicine, Durham, North Carolina, USA.

Funding

PROMISE Trial: Clinical Coordinating CenterR01HL098237 · NHLBI · DUKE UNIVERSITY · PI DOUGLAS, PAMELA SUSAN · 2009 to 2014
$27.3M
PROMISE Trial: SDCCR01HL098236 · NHLBI · DUKE UNIVERSITY · PI LEE, KERRY L · 2009 to 2014
$5.0M
PROMISE Trial: Dx CoreR01HL098305 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI HOFFMANN, UDO · 2009 to 2014
$3.5M
PROMISE Trial: EQOL Coordinating CenterR01HL098235 · NHLBI · DUKE UNIVERSITY · PI MARK, DANIEL B · 2009 to 2014
$1.6M
Patient-centered approaches to diagnosing coronary heart diseaseK23HL116787 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI LADAPO, JOSEPH ABIODUN · 2013 to 2017
$790k
NHLBI NIH HHS K23 HL116787NHLBI NIH HHS R01 HL098235NHLBI NIH HHS R01 HL098236NHLBI NIH HHS R01 HL098237NHLBI NIH HHS R01 HL098305
6 · The paper itself

Abstract

objectivesTo evaluate potential gaps in preventive medical therapy and healthy lifestyle practices among symptomatic patients with suspected coronary artery disease (CAD) seeing primary care physicians and cardiologists and how gaps vary by sociodemographic characteristics and baseline cardiovascular risk.

designCross-sectional study assessing potential preventive gaps.

participants10 003 symptomatic outpatients evaluated by primary care physicians, cardiologists or other specialists for suspected CAD.

settingPROspective Multicenter Imaging Study for Evaluation of Chest Painfrom 2010 to 2014. MEASURES: Primary measures were absence of an antihypertensive, statin or angiotensin-converting enzyme inhibitor/angiotensin receptor blocker for renal protection in patients with hypertension, dyslipidaemia or diabetes, respectively, and being sedentary, smoking or being obese.

resultsPreventive treatment gaps affected 14% of patients with hypertension, 36% of patients with dyslipidaemia and 32% of patients with diabetes. Overall, 49% of patients were sedentary, 18% currently smoked and 48% were obese. Women were significantly more likely to not take a statin for dyslipidaemia and to be sedentary. Patients with lower socioeconomic status were also significantly more likely to not take a statin. Compared with Whites, Blacks were significantly more likely to be obese, while Asians were less likely to smoke or be obese. High-risk patients sometimes experienced larger preventive care gaps than low-risk patients. For patients with dyslipidaemia, the presence of a treatment gap was associated with a higher risk of an adverse event (HR 1.35, 95% CI 1.02 to 1.82).

conclusionsAmong contemporary, symptomatic patients with suspected CAD, significant gaps exist in preventive care and lifestyle practices, and high-risk patients sometimes had larger gaps. Differences by sex, age, race/ethnicity, socioeconomic status and geography are modest but contribute to disparities and have implications for improving opulation health. For patients with dyslipidaemia, the presence of a treatment gap was associated with a higher risk of an adverse event. CLINICAL

trial registrationClinical Trials.gov identifier NCT01174550.

Indexed as

Healthcare DisparitiesIncomeLife StylePreventive MedicineSocial ClassAgedAged, 80 and overAngiotensin-Converting Enzyme InhibitorsAntihypertensive AgentsBody Mass IndexCoronary Artery DiseaseCross-Sectional StudiesExerciseFemaleHumansHypertensionAngiotensin-Converting Enzyme InhibitorsAntihypertensive Agentscardiac stress testingcoronary artery diseasecoronary computed tomography angiographyhealth disparitiessocioeconomics

Identifiers

PMID28965093
PMCPMC5640109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.