Evidence map›Paper›PMID 28964854›Full record

ArticlePreventive medicine2018

Estimating health benefits and cost-savings for achieving the Healthy People 2020 objective of reducing invasive colorectal cancer.

Mei-Chuan Hung, Donatus U Ekwueme, Arica White, Sun Hee Rim, Jessica B King, Jung-Der Wang, Su-Hsin Chang

Abstract read
In one paragraph

Article in Preventive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mei-Chuan HungDivision of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States.
Donatus U EkwuemeDivision of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States. Electronic address: dce3@cdc.gov.
Arica WhiteDivision of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States.
Sun Hee RimDivision of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States.
Jessica B KingDivision of Cancer Prevention and Control, U.S. Centers for Disease Control and Prevention, 4770 Buford Highway, Chamblee Bldg. 107, Chamblee, GA 30341, United States.
Jung-Der WangDepartment of Public Health, National Cheng Kung University College of Medicine, Tainan 704, Taiwan.
Su-Hsin ChangDivision of Public Health Sciences, Department of Surgery, School of Medicine, Washington University in St. Louis, St. Louis, MO 63110, United States.

Funding

Worksite Policies and neighborhood Influences on Obesity and Cancer RiskU54CA155496 · NCI · WASHINGTON UNIVERSITY · PI COLDITZ, GRAHAM A. · 2011 to 2016
$9.0M
OBESITY, COMORBIDITIES, AND ECONOMIC EVALUATIONS OF SURGICAL TREATMENTS OF OBESITK01HS022330 · AHRQ · WASHINGTON UNIVERSITY · PI CHANG, SU-HSIN · 2013 to 2016
$505k
MODELING THE COEXISTENCE OF CHRONIC DISEASES RELATED TO OBESITYR21DK110530 · NIDDK · WASHINGTON UNIVERSITY · PI CHANG, SU-HSIN · 2017 to 2018
$419k
AHRQ HHS K01 HS022330Intramural CDC HHS CC999999NCI NIH HHS U54 CA155496NIDDK NIH HHS R21 DK110530
6 · The paper itself

Abstract

This study aims to quantify the aggregate potential life-years (LYs) saved and healthcare cost-savings if the Healthy People 2020 objective were met to reduce invasive colorectal cancer (CRC) incidence by 15%. We identified patients (n=886,380) diagnosed with invasive CRC between 2001 and 2011 from a nationally representative cancer dataset. We stratified these patients by sex, race/ethnicity, and age. Using these data and data from the 2001-2011 U.S. life tables, we estimated a survival function for each CRC group and the corresponding reference group and computed per-person LYs saved. We estimated per-person annual healthcare cost-savings using the 2008-2012 Medical Expenditure Panel Survey. We calculated aggregate LYs saved and cost-savings by multiplying the reduced number of CRC patients by the per-person LYs saved and lifetime healthcare cost-savings, respectively. We estimated an aggregate of 84,569 and 64,924 LYs saved for men and women, respectively, accounting for healthcare cost-savings of $329.3 and $294.2 million (in 2013$), respectively. Per person, we estimated 6.3 potential LYs saved related to those who developed CRC for both men and women, and healthcare cost-savings of $24,000 for men and $28,000 for women. Non-Hispanic whites and those aged 60-64 had the highest aggregate potential LYs saved and cost-savings. Achieving the HP2020 objective of reducing invasive CRC incidence by 15% by year 2020 would potentially save nearly 150,000 life-years and $624 million on healthcare costs.

Indexed as

Quality-Adjusted Life YearsAgedAge FactorsColorectal NeoplasmsCost SavingsFemaleHealth ExpendituresHealthy People ProgramsHumansMaleMiddle AgedSurveys and QuestionnairesUnited StatesHealthy People 2020Invasive colorectal cancerLifetime healthcare costsLife years (LYs)

Identifiers

PMID28964854
PMCPMC5874792

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.