ArticleCell systems2017
Yeast Creates a Niche for Symbiotic Lactic Acid Bacteria through Nitrogen Overflow.
Article in Cell systems, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 164 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
164 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Contribution ofFrontiers in cellular and infection microbiology · 2021Pooled it
- Niche Construction: A Rational Engineering Strategy for Regulating Microbial Assembly to Enhance Flavor and Bioactivity of Fermented Foods.Comprehensive reviews in food science and food safety · 2026Review
- Obligate cross-feeding of metabolites is common in soil microbial communities.Nature microbiology · 2026Article
- Two-Stage Sequential Fermentation of Oat Drink UsingFood science & nutrition · 2026Article
- Synergistic improvement of flavor development in fermented chili paste through microbial co-fermentation and enzymatic hydrolysis.Food chemistry: X · 2026Article
- Analysis of nutritional components and flavor compounds in naturally fermented, fermentation agent-fermented, and unfermented multi-grain pancakes.Food chemistry: X · 2026Article
- Microbial Interactions and Flavor Modulation in Cabbage Fermentation: Roles ofMolecules (Basel, Switzerland) · 2026Article
- Specificity and longevity of a bacterial interspecies mutual cooperation benefiting organic micropollutant biodegradation.Applied and environmental microbiology · 2026Article
- Impact of Microbial Interactions on Growth and Flavor Profiles of Indigenous Yeasts and Lactic Acid Bacteria in Shanxi Aged Vinegar: Combinatorial Co-Cultures Versus Monocultures.Foods (Basel, Switzerland) · 2026Article
- Burden-aware feedback control of microbial consortia.Nature communications · 2026Article
- In vitro characterization of probiotic properties of isolated and grown co-cultures on halophyte-based substrate.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Structural and Metabolic Remodeling of Mixed Lactic Acid Bacteria-Fermented Wheat Germ and Its In Vitro and In Vivo Digestive Stability.Foods (Basel, Switzerland) · 2026Article
- Bacterial genome reconstruction and community profiling in Neotropical Drosophila.Scientific reports · 2026Article
- Hypersensitivity of chitin degradation to initial species densities due to monomer diffusion.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Wild Yeasts as Reservoirs of Bacterial Diversity: Biotechnological Insights from 16S rRNA Metabarcoding.Foods (Basel, Switzerland) · 2026Article
- Native microorganisms as natural enhancers in craft beer and wine production.Frontiers in microbiology · 2026Review
- From fruit waste to foods via fermentation.Current research in food science · 2026Review
- Dynamic microbiota in water kefir: microbial shift and ecological selection during fermentation.BMC microbiology · 2025Article
- Slower-growing species promote interspecific cooperation and coexistence under acid stress through cross-feeding.Nature communications · 2025Article
- Photosynthetic Biomanufacturing in Mechanically Robust, 3D Printed Hydrogels.ACS synthetic biology · 2025Article
104 more citing papers are in PubMed but not listed here.
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12 authors.
Funding
Abstract
Many microorganisms live in communities and depend on metabolites secreted by fellow community members for survival. Yet our knowledge of interspecies metabolic dependencies is limited to few communities with small number of exchanged metabolites, and even less is known about cellular regulation facilitating metabolic exchange. Here we show how yeast enables growth of lactic acid bacteria through endogenous, multi-component, cross-feeding in a readily established community. In nitrogen-rich environments, Saccharomyces cerevisiae adjusts its metabolism by secreting a pool of metabolites, especially amino acids, and thereby enables survival of Lactobacillus plantarum and Lactococcus lactis. Quantity of the available nitrogen sources and the status of nitrogen catabolite repression pathways jointly modulate this niche creation. We demonstrate how nitrogen overflow by yeast benefits L. plantarum in grape juice, and contributes to emergence of mutualism with L. lactis in a medium with lactose. Our results illustrate how metabolic decisions of an individual species can benefit others.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.