SynthesisSchizophrenia research2018
A widening longevity gap between people with schizophrenia and general population: A literature review and call for action.
Synthesis in Schizophrenia research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- Long-term effects of antipsychotics on mortality in patients with schizophrenia: a systematic review and meta-analysis.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2022Pooled it
- Gut microbiome in serious mental illnesses: A systematic review and critical evaluation.Schizophrenia research · 2021Pooled it
- Overview and systematic review of studies of microbiome in schizophrenia and bipolar disorder.Journal of psychiatric research · 2018Pooled it
- Predictors of Mortality Following a Schizophrenia Spectrum Diagnosis: Evidence From the 20-Year Follow-up of the OPUS Randomized Controlled Trial.Schizophrenia bulletin · 2023Trial
- Psychosocial Interventions, Recovery, and Mediating Mechanisms in Schizophrenia-Spectrum Disorders: A Systematic Review and Meta-Analysis of Longitudinal Studies.Brain sciences · 2026Review
- A Pilot Feasibility Study of a Virtual Lifestyle Intervention for Individuals with Schizophrenia.Community mental health journal · 2026Article
- Change in the life expectancy gap among people with mental illness: a 14-year population-based cohort study in Australia.The Lancet regional health. Western Pacific · 2026Article
- Psychosis as a multisystem disorder of aberrant aging.npj aging · 2026Review
- Cardiometabolic Biomarkers at Age 44-45 in the Psychosis Spectrum: The British National Child Development Study.Schizophrenia bulletin · 2026Article
- Distress as a bridge to suicidality in schizophrenia spectrum disorders: a network-based intervention simulation study.Research square · 2026Article
- Co-production using Theory of Change in the development of the SUCCEED Africa community-based rehabilitation intervention for people living with psychosis in West and Southeast Africa.PLOS mental health · 2026Article
- Behind the Gaps: A Narrative Review of Healthcare Barriers for Individuals with Serious Mental Illness.Healthcare (Basel, Switzerland) · 2025Review
- Childhood adverse events and their association with psychotic symptoms and quality of life in young adults with first episode psychosis and unaffected siblings.Schizophrenia research · 2025Article
- Time trends in life expectancy of people with severe mental illness in Scotland, 2000-2019: population-based study.BJPsych open · 2025Article
- Increased mortality risk in people with schizophrenia in Lithuania 2001-2020.Schizophrenia (Heidelberg, Germany) · 2025Article
- Schizophrenia and physical illness: a coordinated care failure.Frontiers in psychiatry · 2025Article
- Lived experiences of recovery among persons with schizophrenia in Thailand: A qualitative study.Belitung nursing journal · 2025Article
- Predictors and shared traits of longevity within 1 year before death in patients with schizophrenia receiving long-term care: 3-year retrospective cross-sectional study.BJPsych open · 2024Article
- Rest-activity rhythm disruption and metabolic health in schizophrenia: a cross-sectional actigraphy study of community-dwelling people living with schizophrenia and nonpsychiatric comparison participants.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- The impact of menarche on hippocampal mechanisms of severity of psychotic-like experiences in the ABCD study.Psychoneuroendocrinology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
Individuals with schizophrenia have higher mortality rates than the population at large. General mortality rates have declined in developed countries since the early 1970s, extending average lifespan by nearly a decade. This review of eight longitudinal studies of mortality in schizophrenia found that the mean standardized mortality ratio (SMR, a measure of mortality rate in schizophrenia compared to the general population) increased 37%, from 2.2 in the pre-1970s studies to 3.0 in the post-1970s reports. Major changes in societal stigma, healthcare, and economic policy are urgently warranted to ensure that this vulnerable segment of the population participates in the longevity revolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.